STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A2H3CK51Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (174 aa)    
Predicted Functional Partners:
URM1
Ubiquitin-related modifier 1; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target pr [...]
   
 0.794
A0A2H3CNM8
Uncharacterized protein.
   
 0.794
A0A2H3D8F9
Thioredoxin; Belongs to the thioredoxin family.
   
 0.763
A0A2H3DPA7
Thioredoxin.
   
 0.763
A0A2H3DPP3
Uncharacterized protein.
   
 0.763
A0A2H3DRC4
Thioredoxin.
   
 0.763
A0A2H3DYQ2
Thioredoxin.
   
 0.763
A0A2H3CDZ3
Peroxiredoxin.
   
 0.743
A0A2H3CIH9
Uncharacterized protein.
   
 0.743
A0A2H3DA24
Peroxiredoxin.
   
 0.743
Your Current Organism:
Armillaria gallica
NCBI taxonomy Id: 47427
Other names: A. gallica, Armillaria bulbosa, Armillaria lutea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.