A0A2H3DBJ2 protein (Armillaria gallica) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Cooccurrence

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[Homology]

Score

A0A2H3DBJ2

Uncharacterized protein. (477 aa)

Predicted Functional Partners:

A0A2H3CQ09

0.625

A0A2H3E3H3

0.625

A0A2H3DKW7

0.608

A0A2H3EMW5

0.608

A0A2H3E7P5

0.603

A0A2H3EHP7

0.575

A0A2H3E1U1

0.569

A0A2H3DCZ5

0.563

A0A2H3E9J5

0.563

A0A2H3E429

0.551

Your Current Organism:

Armillaria gallica

NCBI taxonomy Id: 47427
Other names: A. gallica, Armillaria bulbosa, Armillaria lutea

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A2H3CQ09	A0A2H3DBJ2	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.625
A0A2H3CQ09	A0A2H3E1U1	ANK_REP_REGION domain-containing protein.	Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family.	0.674
A0A2H3CQ09	A0A2H3E3H3	ANK_REP_REGION domain-containing protein.	Ankyrin.	0.640
A0A2H3CQ09	A0A2H3E7P5	ANK_REP_REGION domain-containing protein.	Mov34-domain-containing protein.	0.648
A0A2H3CQ09	A0A2H3E9J5	ANK_REP_REGION domain-containing protein.	14-3-3-like protein; Belongs to the 14-3-3 family.	0.907
A0A2H3CQ09	A0A2H3EHP7	ANK_REP_REGION domain-containing protein.	14-3-3 protein; Belongs to the 14-3-3 family.	0.907
A0A2H3DBJ2	A0A2H3CQ09	Uncharacterized protein.	ANK_REP_REGION domain-containing protein.	0.625
A0A2H3DBJ2	A0A2H3DCZ5	Uncharacterized protein.	MRG-domain-containing protein.	0.563
A0A2H3DBJ2	A0A2H3DKW7	Uncharacterized protein.	LAG1-DNAbind-domain-containing protein.	0.608
A0A2H3DBJ2	A0A2H3E1U1	Uncharacterized protein.	Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family.	0.569
A0A2H3DBJ2	A0A2H3E3H3	Uncharacterized protein.	Ankyrin.	0.625
A0A2H3DBJ2	A0A2H3E429	Uncharacterized protein.	Uncharacterized protein.	0.551
A0A2H3DBJ2	A0A2H3E7P5	Uncharacterized protein.	Mov34-domain-containing protein.	0.603
A0A2H3DBJ2	A0A2H3E9J5	Uncharacterized protein.	14-3-3-like protein; Belongs to the 14-3-3 family.	0.563
A0A2H3DBJ2	A0A2H3EHP7	Uncharacterized protein.	14-3-3 protein; Belongs to the 14-3-3 family.	0.575
A0A2H3DBJ2	A0A2H3EMW5	Uncharacterized protein.	Beta-trefoil.	0.608
A0A2H3DCZ5	A0A2H3DBJ2	MRG-domain-containing protein.	Uncharacterized protein.	0.563
A0A2H3DKW7	A0A2H3DBJ2	LAG1-DNAbind-domain-containing protein.	Uncharacterized protein.	0.608
A0A2H3DKW7	A0A2H3EMW5	LAG1-DNAbind-domain-containing protein.	Beta-trefoil.	0.496
A0A2H3E1U1	A0A2H3CQ09	Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family.	ANK_REP_REGION domain-containing protein.	0.674

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

31

PPI enrichment p-value:

2.05e-05

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006123

Mitochondrial electron transport, cytochrome c to oxygen

2 of 8

2.93

1.67

0.0033

GO:0032465

Regulation of cytokinesis

2 of 12

2.75

1.52

0.0054

GO:0006122

Mitochondrial electron transport, ubiquinol to cytochrome c

2 of 12

2.75

1.52

0.0054

GO:0007052

Mitotic spindle organization

2 of 25

2.43

1.21

0.0148

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0035175

Histone kinase activity (H3-S10 specific)

2 of 2

3.53

2.09

0.00083

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0032133

Chromosome passenger complex

2 of 2

3.53

2.35

0.00035

GO:0051233

Spindle midzone

2 of 5

3.13

2.17

0.00061

GO:0005758

Mitochondrial intermembrane space

2 of 24

2.45

1.45

0.0063

GO:0005876

Spindle microtubule

2 of 32

2.33

1.4

0.0072

GO:0070469

Respirasome

2 of 89

1.88

0.92

0.0338

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:37175542

(2023) Apostasia Mitochondrial Genome Analysis and Monocot Mitochondria Phylogenomics.

2 of 2

3.53

2.79

7.81e-05

PMID:36463111

(2022) Comparative analysis of mitochondrial genomes reveals marine adaptation in seagrasses.

2 of 2

3.53

2.79

7.81e-05

PMID:31547213

(2019) Comparison of Whole Plastome Sequences between Thermogenic Skunk Cabbage Symplocarpus renifolius and Nonthermogenic S. nipponicus (Orontioideae; Araceae) in East Asia.

2 of 2

3.53

2.79

7.81e-05

PMID:24428220

(2014) Halorhabdus tiamatea: proteogenomics and glycosidase activity measurements identify the first cultivated euryarchaeon from a deep-sea anoxic brine lake as potential polysaccharide degrader.

2 of 2

3.53

2.79

7.81e-05

PMID:23637852

(2013) The complete sequence of the mitochondrial genome of Butomus umbellatus--a member of an early branching lineage of monocotyledons.

2 of 2

3.53

2.79

7.81e-05

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:7007

Aurora kinase-like, and PIR2-like, helical domain

2 of 6

3.05

1.45

0.0072

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map05132

Salmonella infection

2 of 36

2.28

1.38

0.0075

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-111471

Apoptotic factor-mediated response

2 of 2

3.53

2.35

0.00035

MAP-111457

Release of apoptotic factors from the mitochondria

2 of 2

3.53

2.35

0.00035

MAP-5620971

Pyroptosis

2 of 3

3.35

2.34

0.00035

MAP-5218859

Regulated Necrosis

2 of 7

2.99

2.26

0.00043

MAP-109606

Intrinsic Pathway for Apoptosis

2 of 23

2.47

1.71

0.0025

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0032133

Chromosome passenger complex

2 of 5

3.13

1.86

0.0018

GOCC:0051233

Spindle midzone

2 of 7

2.99

1.85

0.0018

GOCC:0005758

Mitochondrial intermembrane space

2 of 34

2.3

1.14

0.0184

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0679

Respiratory chain

2 of 16

2.63

1.66

0.0032

KW-0496

Mitochondrion

2 of 75

1.96

1.07

0.0200

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00034

Cytochrome c

2 of 2

3.53

2.11

0.00079

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR030616

Aurora kinase-like

2 of 2

3.53

1.79

0.0023

IPR002327

Cytochrome c, class IA/ IB

2 of 2

3.53

1.79

0.0023

IPR036909

Cytochrome c-like domain superfamily

2 of 6

3.05

1.65

0.0036

IPR009056

Cytochrome c-like domain

2 of 7

2.99

1.65

0.0036

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