STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NTH1-3Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family. (366 aa)    
Predicted Functional Partners:
ARMOST_03826
DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family.
  
 0.993
ARMOST_19149
Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.
  
 
 0.760
ARMOST_09667
FPG_CAT domain-containing protein.
   
  
 0.715
ARMOST_19082
Uncharacterized protein.
  
 
 0.714
ARMOST_20998
Uncharacterized protein.
  
 
 0.714
ARMOST_21000
Related to Probable endonuclease 4.
  
 
 0.714
ARMOST_16338
Related to DNA mismatch repair protein.
   
 
 0.680
UNG1
Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
   
 0.627
UNG1-2
Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
   
 0.627
ARMOST_16294
Adenosylhomocysteinase.
   
 
  0.617
Your Current Organism:
Armillaria ostoyae
NCBI taxonomy Id: 47428
Other names: A. ostoyae, Armillaria sp. NABS1, Armillariella ostoyae
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.