STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFS18172.1Hydrogenase large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (565 aa)    
Predicted Functional Partners:
SFS18163.1
Hydrogenase small subunit.
 
 0.999
hypA
Hydrogenase nickel incorporation protein HypA/HybF; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.997
SFS18174.1
Hydrogenase maturation protease.
 
 0.990
SFS18188.1
Hydrogenase maturation protein HypD.
 
 
 0.964
SFS18183.1
Hydrogenase maturation protein, carbamoyltransferase HypF.
 
 
 
 0.960
SFS18180.1
Hydrogenase nickel incorporation protein HypB.
 
   
 0.956
SFS18191.1
Hydrogenase maturation protein, carbamoyl dehydratase HypE.
 
   
 0.955
SFS18166.1
[NiFe]-hydrogenase II apoprotein, ferredoxin-type subunit.
 
 
 0.949
SFS18185.1
Hydrogenase expression/formation protein HypC.
 
 
 0.941
SFS18169.1
Ni/Fe-hydrogenase 2 integral membrane subunit HybB.
 
  
 0.940
Your Current Organism:
Granulicella pectinivorans
NCBI taxonomy Id: 474950
Other names: Acidobacteria bacterium TPB6011, DSM 21001, G. pectinivorans, Granulicella pectinivorans Pankratov and Dedysh 2010, VKM B-2509, strain TPB6011
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