STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gprSpore protease; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. (297 aa)    
Predicted Functional Partners:
SEM95138.1
Stage V sporulation protein AD.
  
  
 0.946
SEM95117.1
Stage V sporulation protein AC.
  
  
 0.884
SEM95246.1
Stage II sporulation protein P.
 
    0.858
SEN02389.1
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
   
 0.847
SEM46534.1
Small, acid-soluble spore protein, alpha/beta type.
  
  
 0.838
SEM80810.1
RNA polymerase, sigma 27/28 subunit, RpsK/SigK; Non-canonical start codon; manually curated.
  
    0.837
spoIIAB
Stage II sporulation protein AB (anti-sigma F factor); Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
   
 0.823
SEM55207.1
Two-component system, response regulator, stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.815
SEM55193.1
Stage IV sporulation protein B.
  
    0.809
SEM81039.1
AbrB family transcriptional regulator, stage V sporulation protein T.
  
  
 0.789
Your Current Organism:
Hydrogenoanaerobacterium saccharovorans
NCBI taxonomy Id: 474960
Other names: AS 1.5070, Clostridium sp. SW512, Clostridium sp. W72, H. saccharovorans, Hydrogenoanaerobacterium saccharovorans Song and Dong 2009, JCM 14861, strain SW512
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