STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEN10338.1Histidinol-phosphatase (PHP family); Belongs to the PHP hydrolase family. HisK subfamily. (275 aa)    
Predicted Functional Partners:
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
 
 
 0.881
hisI
phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family.
  
 
 0.845
SEM57639.1
Histidinol-phosphate aminotransferase.
  
 
 0.823
hisB
Imidazoleglycerol-phosphate dehydratase.
  
 
 0.798
SEM65100.1
L-threonine O-3-phosphate decarboxylase.
  
 
 0.623
SEN10314.1
L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.
       0.516
hisH
Glutamine amidotransferase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
  
  
 0.490
SEN10298.1
L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.
       0.483
ybeY
Probable rRNA maturation factor; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
   
    0.432
Your Current Organism:
Hydrogenoanaerobacterium saccharovorans
NCBI taxonomy Id: 474960
Other names: AS 1.5070, Clostridium sp. SW512, Clostridium sp. W72, H. saccharovorans, Hydrogenoanaerobacterium saccharovorans Song and Dong 2009, JCM 14861, strain SW512
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