KON98572.1 protein (Aneurinibacillus migulanus)

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second shell of interactors

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a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

KON98572.1

Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial solute-binding protein 3 family. (264 aa)

Predicted Functional Partners:

KON98335.1

0.996

KON93256.1

0.989

KON93257.1

0.989

KON95299.1

0.986

KON97501.1

0.986

KON84207.1

0.986

KON98357.1

0.878

KON95300.1

0.878

KON93255.1

0.878

KON97500.1

0.877

Your Current Organism:

Aneurinibacillus migulanus

NCBI taxonomy Id: 47500
Other names: A. migulanus, ATCC 9999, Bacillus migulanus, CIP 103841, DSM 2895, IFO 15520, IFO 3864, JCM 8504, LMG 15427, LMG:15427, NBRC 15520, NCIB 7096, NCIB:7096, NCTC 7096, strain B0270

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KON84207.1	KON93255.1	AF333_30125	AF333_26745	Amino acid ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.984
KON84207.1	KON93256.1	AF333_30125	AF333_26755	Amino acid ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.484
KON84207.1	KON93257.1	AF333_30125	AF333_26760	Amino acid ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.504
KON84207.1	KON95299.1	AF333_30125	AF333_07195	Amino acid ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Cystine transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.488
KON84207.1	KON95300.1	AF333_30125	AF333_07200	Amino acid ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Amino acid ABC transporter ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.987
KON84207.1	KON97500.1	AF333_30125	AF333_20545	Amino acid ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Amino acid ABC transporter ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.987
KON84207.1	KON97501.1	AF333_30125	AF333_20550	Amino acid ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Cystine transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.480
KON84207.1	KON98335.1	AF333_30125	AF333_03150	Amino acid ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Amino acid ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.474
KON84207.1	KON98357.1	AF333_30125	AF333_04330	Amino acid ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.986
KON84207.1	KON98572.1	AF333_30125	AF333_16550	Amino acid ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial solute-binding protein 3 family.	0.986
KON93255.1	KON84207.1	AF333_26745	AF333_30125	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Amino acid ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.984
KON93255.1	KON93256.1	AF333_26745	AF333_26755	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.994
KON93255.1	KON93257.1	AF333_26745	AF333_26760	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.993
KON93255.1	KON95299.1	AF333_26745	AF333_07195	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Cystine transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.973
KON93255.1	KON97501.1	AF333_26745	AF333_20550	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Cystine transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.980
KON93255.1	KON98335.1	AF333_26745	AF333_03150	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Amino acid ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.995
KON93255.1	KON98572.1	AF333_26745	AF333_16550	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial solute-binding protein 3 family.	0.878
KON93256.1	KON84207.1	AF333_26755	AF333_30125	Glutamine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Amino acid ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.484
KON93256.1	KON93255.1	AF333_26755	AF333_26745	Glutamine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.994
KON93256.1	KON93257.1	AF333_26755	AF333_26760	Glutamine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.997

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Network Stats

number of nodes:

11

number of edges:

18

average node degree:

3.27

avg. local clustering coefficient:

0.895

expected number of edges:

21

PPI enrichment p-value:

0.759

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0042843

D-xylose catabolic process

5 of 6

3.02

5.28

1.75e-10

GO:0042559

Pteridine-containing compound biosynthetic process

4 of 13

2.59

3.49

2.53e-07

GO:0006729

Tetrahydrobiopterin biosynthetic process

3 of 5

2.88

2.85

6.01e-06

GO:0044282

Small molecule catabolic process

6 of 215

1.54

2.06

2.33e-06

GO:0019568

Arabinose catabolic process

2 of 2

3.1

1.82

0.00052

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004032

alditol:NADP+ 1-oxidoreductase activity

5 of 7

2.95

5.32

1.35e-10

GO:0016616

Oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

6 of 131

1.76

2.74

1.46e-07

GO:0016491

Oxidoreductase activity

9 of 913

1.09

1.33

3.18e-07

GO:0016646

Oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor

2 of 13

2.29

1.05

0.0116

GO:0003824

Catalytic activity

11 of 3985

0.54

0.46

0.00026

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:10292

Mixed, incl. Tetrahydrobiopterin metabolic process, and D-xylose catabolic process

7 of 15

2.77

7.39

5.11e-15

CL:10310

Tetrahydrobiopterin metabolic process, and Oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor

4 of 6

2.92

4.11

2.63e-08

CL:11394

Pyrimidine deoxyribonucleoside triphosphate metabolic process, and Dihydrofolate metabolic process

2 of 5

2.7

1.26

0.0052

CL:10294

Alditol catabolic process, and D-xylose catabolic process

2 of 5

2.7

1.26

0.0052

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00790

Folate biosynthesis

5 of 50

2.1

3.41

5.51e-08

map00670

One carbon pool by folate

2 of 16

2.2

1.26

0.0043

map00561

Glycerolipid metabolism

2 of 54

1.67

0.76

0.0317

map01100

Metabolic pathways

11 of 2462

0.75

4.36e-07

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-196108

Pregnenolone biosynthesis

5 of 7

2.95

5.43

8.23e-11

MAP-193807

Synthesis of bile acids and bile salts via 27-hydroxycholesterol

5 of 7

2.95

5.43

8.23e-11

MAP-193144

Estrogen biosynthesis

5 of 8

2.89

5.4

8.23e-11

MAP-2162123

Synthesis of Prostaglandins (PG) and Thromboxanes (TX)

5 of 11

2.76

5.25

1.13e-10

MAP-5652227

Fructose biosynthesis

5 of 13

2.68

5.1

1.78e-10

(more ...)

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00248

Aldo/keto reductase family

5 of 38

2.22

3.4

1.16e-07

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR018170

Aldo/keto reductase, conserved site

5 of 8

2.89

5.03

4.34e-10

IPR020471

Aldo-keto reductase

5 of 16

2.59

4.41

3.42e-09

IPR036812

NADP-dependent oxidoreductase domain superfamily

5 of 38

2.22

3.42

1.07e-07

IPR023210

NADP-dependent oxidoreductase domain

5 of 38

2.22

3.42

1.07e-07

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