STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMC72647.1S1/P1 Nuclease. (270 aa)    
Predicted Functional Partners:
SMC72621.1
Protein of unknown function.
       0.789
SMC72635.1
Protein tyrosine phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
       0.789
guaA
GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
    
  0.763
SMD00951.1
Nicotinamide-nucleotide amidase; Belongs to the CinA family.
    
  0.751
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.669
SMC72660.1
Hypothetical protein.
       0.646
fumC
Fumarase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
       0.628
SMC94079.1
5'-nucleotidase, C-terminal domain.
    
 0.529
SMC94086.1
5'-nucleotidase; Belongs to the 5'-nucleotidase family.
    
 0.529
SMC72607.1
Hypothetical protein.
       0.519
Your Current Organism:
Pedobacter nyackensis
NCBI taxonomy Id: 475255
Other names: DSM 19625, LMG 24260, LMG:24260, P. nyackensis, Pedobacter nyackensis Gordon et al. 2009, strain NWG-II14
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.