STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMC80866.1FKBP-type peptidyl-prolyl cis-trans isomerase FkpA. (163 aa)    
Predicted Functional Partners:
SMC74063.1
Molecular chaperone HtpG.
   
 0.940
tgt
tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...]
    
  0.844
SMC80868.1
FKBP-type peptidyl-prolyl cis-trans isomerase.
 
     0.837
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.802
SMC95419.1
Hypothetical chaperone protein.
   
 0.802
SMC97449.1
Molecular chaperone HscA; Belongs to the heat shock protein 70 family.
   
 0.802
SMC80018.1
Protein involved in gliding motility SprA.
    
 
 0.691
SMC80366.1
Aspartate kinase.
  
   0.568
SMC80863.1
Acyl-CoA dehydrogenase.
   
   0.536
SMC80860.1
acetyl-CoA acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
    0.532
Your Current Organism:
Pedobacter nyackensis
NCBI taxonomy Id: 475255
Other names: DSM 19625, LMG 24260, LMG:24260, P. nyackensis, Pedobacter nyackensis Gordon et al. 2009, strain NWG-II14
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