node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SMC72501.1 | SMC75183.1 | SAMN04488101_102484 | SAMN04488101_102715 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). | methylmalonyl-CoA mutase, C-terminal domain. | 0.888 |
SMC72501.1 | SMC82538.1 | SAMN04488101_102484 | SAMN04488101_103324 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). | methylmalonyl-CoA mutase. | 0.888 |
SMC72501.1 | SMC95458.1 | SAMN04488101_102484 | SAMN04488101_106237 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). | Citrate synthase; Belongs to the citrate synthase family. | 0.975 |
SMC72501.1 | icmF | SAMN04488101_102484 | SAMN04488101_1013 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). | methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | 0.710 |
SMC72501.1 | mdh | SAMN04488101_102484 | SAMN04488101_11157 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.614 |
SMC72501.1 | pckA | SAMN04488101_102484 | SAMN04488101_11071 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. | 0.948 |
SMC72501.1 | sucC | SAMN04488101_102484 | SAMN04488101_1043 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). | succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.982 |
SMC72501.1 | sucD | SAMN04488101_102484 | SAMN04488101_116119 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). | succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.974 |
SMC72730.1 | SMC75183.1 | SAMN04488101_102503 | SAMN04488101_102715 | LAO/AO transport system kinase. | methylmalonyl-CoA mutase, C-terminal domain. | 0.949 |
SMC72730.1 | SMC82538.1 | SAMN04488101_102503 | SAMN04488101_103324 | LAO/AO transport system kinase. | methylmalonyl-CoA mutase. | 0.969 |
SMC72730.1 | SMD17452.1 | SAMN04488101_102503 | SAMN04488101_12327 | LAO/AO transport system kinase. | methylmalonyl-CoA epimerase. | 0.908 |
SMC72730.1 | icmF | SAMN04488101_102503 | SAMN04488101_1013 | LAO/AO transport system kinase. | methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | 0.913 |
SMC75183.1 | SMC72501.1 | SAMN04488101_102715 | SAMN04488101_102484 | methylmalonyl-CoA mutase, C-terminal domain. | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). | 0.888 |
SMC75183.1 | SMC72730.1 | SAMN04488101_102715 | SAMN04488101_102503 | methylmalonyl-CoA mutase, C-terminal domain. | LAO/AO transport system kinase. | 0.949 |
SMC75183.1 | SMC82538.1 | SAMN04488101_102715 | SAMN04488101_103324 | methylmalonyl-CoA mutase, C-terminal domain. | methylmalonyl-CoA mutase. | 0.999 |
SMC75183.1 | SMC95458.1 | SAMN04488101_102715 | SAMN04488101_106237 | methylmalonyl-CoA mutase, C-terminal domain. | Citrate synthase; Belongs to the citrate synthase family. | 0.896 |
SMC75183.1 | SMD17452.1 | SAMN04488101_102715 | SAMN04488101_12327 | methylmalonyl-CoA mutase, C-terminal domain. | methylmalonyl-CoA epimerase. | 0.997 |
SMC75183.1 | icmF | SAMN04488101_102715 | SAMN04488101_1013 | methylmalonyl-CoA mutase, C-terminal domain. | methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | 0.997 |
SMC75183.1 | mdh | SAMN04488101_102715 | SAMN04488101_11157 | methylmalonyl-CoA mutase, C-terminal domain. | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.902 |
SMC75183.1 | pckA | SAMN04488101_102715 | SAMN04488101_11071 | methylmalonyl-CoA mutase, C-terminal domain. | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. | 0.902 |