node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OOR87343.1 | fdx | B0182_12825 | B0182_12780 | Rrf2 family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ferredoxin, 2Fe-2S type, ISC system; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.578 |
OOR87343.1 | hscA | B0182_12825 | B0182_12785 | Rrf2 family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.436 |
OOR87343.1 | hscB | B0182_12825 | B0182_12790 | Rrf2 family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe-S protein assembly co-chaperone HscB; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HscB family. | 0.879 |
OOR87343.1 | iscA | B0182_12825 | B0182_12795 | Rrf2 family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Iron-sulfur cluster assembly protein IscA; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family. | 0.742 |
OOR87343.1 | iscS | B0182_12825 | B0182_12820 | Rrf2 family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | IscS subfamily cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.996 |
OOR87343.1 | nfuA | B0182_12825 | B0182_10675 | Rrf2 family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe-S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.592 |
OOR87343.1 | nifU | B0182_12825 | B0182_12800 | Rrf2 family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe-S cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.917 |
dnaK | fdx | B0182_03700 | B0182_12780 | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Ferredoxin, 2Fe-2S type, ISC system; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.512 |
dnaK | hscB | B0182_03700 | B0182_12790 | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Fe-S protein assembly co-chaperone HscB; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HscB family. | 0.780 |
dnaK | iscS | B0182_03700 | B0182_12820 | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | IscS subfamily cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.468 |
dnaK | nfuA | B0182_03700 | B0182_10675 | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Fe-S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.515 |
dnaK | nifU | B0182_03700 | B0182_12800 | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Fe-S cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.820 |
erpA | hscB | B0182_11010 | B0182_12790 | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. | Fe-S protein assembly co-chaperone HscB; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HscB family. | 0.579 |
erpA | iscS | B0182_11010 | B0182_12820 | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. | IscS subfamily cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.482 |
erpA | nfuA | B0182_11010 | B0182_10675 | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. | Fe-S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.619 |
erpA | nifU | B0182_11010 | B0182_12800 | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. | Fe-S cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.699 |
fdx | OOR87343.1 | B0182_12780 | B0182_12825 | Ferredoxin, 2Fe-2S type, ISC system; Derived by automated computational analysis using gene prediction method: Protein Homology. | Rrf2 family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.578 |
fdx | dnaK | B0182_12780 | B0182_03700 | Ferredoxin, 2Fe-2S type, ISC system; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.512 |
fdx | hscA | B0182_12780 | B0182_12785 | Ferredoxin, 2Fe-2S type, ISC system; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.941 |
fdx | hscB | B0182_12780 | B0182_12790 | Ferredoxin, 2Fe-2S type, ISC system; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe-S protein assembly co-chaperone HscB; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HscB family. | 0.979 |