| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| acnA | rplC | ICMP_088 | ICMP_252 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.547 |
| acnA | rplM | ICMP_088 | ICMP_162 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.537 |
| acnA | rplO | ICMP_088 | ICMP_271 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.561 |
| acnA | rplQ | ICMP_088 | ICMP_278 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 50S ribosomal protein L17. | 0.717 |
| acnA | rplS | ICMP_088 | ICMP_546 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.786 |
| acnA | rpsE | ICMP_088 | ICMP_269 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. | 0.560 |
| acnA | rpsK | ICMP_088 | ICMP_275 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. | 0.576 |
| acnA | rpsP | ICMP_088 | ICMP_549 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. | 0.723 |
| acnA | sodA | ICMP_088 | ICMP_023 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Superoxide dismutase(Mn); Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | 0.830 |
| rplC | acnA | ICMP_252 | ICMP_088 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 0.547 |
| rplC | rplM | ICMP_252 | ICMP_162 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.999 |
| rplC | rplO | ICMP_252 | ICMP_271 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.999 |
| rplC | rplQ | ICMP_252 | ICMP_278 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 50S ribosomal protein L17. | 0.997 |
| rplC | rplS | ICMP_252 | ICMP_546 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.994 |
| rplC | rpoB | ICMP_252 | ICMP_525 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.976 |
| rplC | rpsE | ICMP_252 | ICMP_269 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. | 0.999 |
| rplC | rpsK | ICMP_252 | ICMP_275 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. | 0.998 |
| rplC | rpsP | ICMP_252 | ICMP_549 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. | 0.995 |
| rplC | sodA | ICMP_252 | ICMP_023 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | Superoxide dismutase(Mn); Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | 0.789 |
| rplM | acnA | ICMP_162 | ICMP_088 | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 0.537 |