| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ICMP_215 | cvpA | ICMP_215 | ICMP_044 | Hypothetical protein; N-terminal transmembrane region have sequence similarity to sppA. | Membrane protein required for colicin V production. | 0.543 |
| ICMP_215 | folC | ICMP_215 | ICMP_043 | Hypothetical protein; N-terminal transmembrane region have sequence similarity to sppA. | Bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10- formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives. | 0.559 |
| ICMP_215 | ftsQ | ICMP_215 | ICMP_392 | Hypothetical protein; N-terminal transmembrane region have sequence similarity to sppA. | Membrane anchored protein; Involved in growth of wall at septum. | 0.720 |
| accD | cvpA | ICMP_042 | ICMP_044 | acetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. | Membrane protein required for colicin V production. | 0.563 |
| accD | folC | ICMP_042 | ICMP_043 | acetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. | Bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10- formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives. | 0.859 |
| accD | yhiQ | ICMP_042 | ICMP_041 | acetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. | Predicted SAM-dependent methyltransferase; Specifically methylates the guanosine in position 1516 of 16S rRNA. | 0.400 |
| cvpA | ICMP_215 | ICMP_044 | ICMP_215 | Membrane protein required for colicin V production. | Hypothetical protein; N-terminal transmembrane region have sequence similarity to sppA. | 0.543 |
| cvpA | accD | ICMP_044 | ICMP_042 | Membrane protein required for colicin V production. | acetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. | 0.563 |
| cvpA | folC | ICMP_044 | ICMP_043 | Membrane protein required for colicin V production. | Bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10- formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives. | 0.578 |
| cvpA | ftsQ | ICMP_044 | ICMP_392 | Membrane protein required for colicin V production. | Membrane anchored protein; Involved in growth of wall at septum. | 0.464 |
| cvpA | purH | ICMP_044 | ICMP_521 | Membrane protein required for colicin V production. | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. | 0.482 |
| cvpA | secE | ICMP_044 | ICMP_531 | Membrane protein required for colicin V production. | Translocase; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. | 0.477 |
| cvpA | ubiX | ICMP_044 | ICMP_045 | Membrane protein required for colicin V production. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.516 |
| cvpA | yhiQ | ICMP_044 | ICMP_041 | Membrane protein required for colicin V production. | Predicted SAM-dependent methyltransferase; Specifically methylates the guanosine in position 1516 of 16S rRNA. | 0.410 |
| folC | ICMP_215 | ICMP_043 | ICMP_215 | Bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10- formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives. | Hypothetical protein; N-terminal transmembrane region have sequence similarity to sppA. | 0.559 |
| folC | accD | ICMP_043 | ICMP_042 | Bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10- formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives. | acetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. | 0.859 |
| folC | cvpA | ICMP_043 | ICMP_044 | Bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10- formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives. | Membrane protein required for colicin V production. | 0.578 |
| folC | yhiQ | ICMP_043 | ICMP_041 | Bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10- formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives. | Predicted SAM-dependent methyltransferase; Specifically methylates the guanosine in position 1516 of 16S rRNA. | 0.400 |
| ftsQ | ICMP_215 | ICMP_392 | ICMP_215 | Membrane anchored protein; Involved in growth of wall at septum. | Hypothetical protein; N-terminal transmembrane region have sequence similarity to sppA. | 0.720 |
| ftsQ | cvpA | ICMP_392 | ICMP_044 | Membrane anchored protein; Involved in growth of wall at septum. | Membrane protein required for colicin V production. | 0.464 |