| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| fbaA | gapA | ICMP_152 | ICMP_220 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.994 |
| fbaA | glk | ICMP_152 | ICMP_105 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Glucokinase; Belongs to the bacterial glucokinase family. | 0.872 |
| fbaA | pgi | ICMP_152 | ICMP_621 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.963 |
| fbaA | talB | ICMP_152 | ICMP_310 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Transaldolase B; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. | 0.955 |
| fbaA | tktA | ICMP_152 | ICMP_154 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.966 |
| fbaA | zwf | ICMP_152 | ICMP_227 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.857 |
| galP | glk | ICMP_559 | ICMP_105 | D-galactose (H+ symport)transporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. | Glucokinase; Belongs to the bacterial glucokinase family. | 0.519 |
| gapA | fbaA | ICMP_220 | ICMP_152 | Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 0.994 |
| gapA | glk | ICMP_220 | ICMP_105 | Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Glucokinase; Belongs to the bacterial glucokinase family. | 0.544 |
| gapA | guaA | ICMP_220 | ICMP_077 | Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | 0.663 |
| gapA | ilvD | ICMP_220 | ICMP_036 | Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.414 |
| gapA | pgi | ICMP_220 | ICMP_621 | Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.958 |
| gapA | talB | ICMP_220 | ICMP_310 | Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Transaldolase B; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. | 0.895 |
| gapA | tktA | ICMP_220 | ICMP_154 | Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.967 |
| gapA | zwf | ICMP_220 | ICMP_227 | Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.908 |
| glk | fbaA | ICMP_105 | ICMP_152 | Glucokinase; Belongs to the bacterial glucokinase family. | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 0.872 |
| glk | galP | ICMP_105 | ICMP_559 | Glucokinase; Belongs to the bacterial glucokinase family. | D-galactose (H+ symport)transporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. | 0.519 |
| glk | gapA | ICMP_105 | ICMP_220 | Glucokinase; Belongs to the bacterial glucokinase family. | Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.544 |
| glk | guaA | ICMP_105 | ICMP_077 | Glucokinase; Belongs to the bacterial glucokinase family. | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | 0.493 |
| glk | ilvD | ICMP_105 | ICMP_036 | Glucokinase; Belongs to the bacterial glucokinase family. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.534 |