| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| gntY | grxC | ICMP_115 | ICMP_647 | Predicted gluconate transport associated protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | 0.712 |
| gntY | ilvD | ICMP_115 | ICMP_036 | Predicted gluconate transport associated protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.728 |
| gntY | iscS | ICMP_115 | ICMP_069 | Predicted gluconate transport associated protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | Cysteine desulfurase. | 0.981 |
| gntY | nuoI | ICMP_115 | ICMP_055 | Predicted gluconate transport associated protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | NADH:ubiquinone oxidoreductase chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. | 0.882 |
| gntY | sdhB | ICMP_115 | ICMP_486 | Predicted gluconate transport associated protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | Succinate dehydrogenase FeS subunit. | 0.887 |
| gntY | sufB | ICMP_115 | ICMP_447 | Predicted gluconate transport associated protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | Component of SufBCD complex. | 0.744 |
| gntY | sufC | ICMP_115 | ICMP_446 | Predicted gluconate transport associated protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | Cysteine desulfurase ATPase component. | 0.764 |
| gntY | sufD | ICMP_115 | ICMP_445 | Predicted gluconate transport associated protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | Component of SufBCD complex. | 0.744 |
| gntY | ydhD | ICMP_115 | ICMP_439 | Predicted gluconate transport associated protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | Hypothetical protein; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.836 |
| gntY | yfaE | ICMP_115 | ICMP_062 | Predicted gluconate transport associated protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | Predicted 2Fe-2S cluster-containing protein. | 0.779 |
| grxC | gntY | ICMP_647 | ICMP_115 | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | Predicted gluconate transport associated protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.712 |
| grxC | ydhD | ICMP_647 | ICMP_439 | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | Hypothetical protein; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.433 |
| ilvD | gntY | ICMP_036 | ICMP_115 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | Predicted gluconate transport associated protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.728 |
| ilvD | nuoI | ICMP_036 | ICMP_055 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | NADH:ubiquinone oxidoreductase chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. | 0.548 |
| ilvD | sdhB | ICMP_036 | ICMP_486 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | Succinate dehydrogenase FeS subunit. | 0.533 |
| iscS | gntY | ICMP_069 | ICMP_115 | Cysteine desulfurase. | Predicted gluconate transport associated protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.981 |
| iscS | yfaE | ICMP_069 | ICMP_062 | Cysteine desulfurase. | Predicted 2Fe-2S cluster-containing protein. | 0.981 |
| nuoI | gntY | ICMP_055 | ICMP_115 | NADH:ubiquinone oxidoreductase chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. | Predicted gluconate transport associated protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.882 |
| nuoI | ilvD | ICMP_055 | ICMP_036 | NADH:ubiquinone oxidoreductase chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.548 |
| nuoI | sdhB | ICMP_055 | ICMP_486 | NADH:ubiquinone oxidoreductase chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. | Succinate dehydrogenase FeS subunit. | 0.910 |