| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cysC | cysD | ICMP_123 | ICMP_125 | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | Sulfate adenylyltransferase subunit 2. | 0.999 |
| cysC | cysG | ICMP_123 | ICMP_126 | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | Uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.989 |
| cysC | cysH | ICMP_123 | ICMP_127 | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. | 0.998 |
| cysC | cysI | ICMP_123 | ICMP_128 | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | Sulfite reductase beta subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.940 |
| cysC | cysJ | ICMP_123 | ICMP_129 | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | Sulfite reductase alpha subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. | 0.903 |
| cysC | cysK | ICMP_123 | ICMP_112 | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | Cysteine synthase A, O-acetylserine sulfhydrolase A subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.778 |
| cysC | cysN | ICMP_123 | ICMP_124 | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.999 |
| cysC | cysQ | ICMP_123 | ICMP_169 | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. | 0.934 |
| cysC | tufB | ICMP_123 | ICMP_250 | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | Protein chain elongation factor EF-Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. | 0.829 |
| cysC | tufB-2 | ICMP_123 | ICMP_532 | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | Protein chain elongation factor EF-Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. | 0.896 |
| cysD | cysC | ICMP_125 | ICMP_123 | Sulfate adenylyltransferase subunit 2. | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.999 |
| cysD | cysG | ICMP_125 | ICMP_126 | Sulfate adenylyltransferase subunit 2. | Uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.984 |
| cysD | cysH | ICMP_125 | ICMP_127 | Sulfate adenylyltransferase subunit 2. | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. | 0.953 |
| cysD | cysI | ICMP_125 | ICMP_128 | Sulfate adenylyltransferase subunit 2. | Sulfite reductase beta subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.924 |
| cysD | cysJ | ICMP_125 | ICMP_129 | Sulfate adenylyltransferase subunit 2. | Sulfite reductase alpha subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. | 0.941 |
| cysD | cysK | ICMP_125 | ICMP_112 | Sulfate adenylyltransferase subunit 2. | Cysteine synthase A, O-acetylserine sulfhydrolase A subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.833 |
| cysD | cysN | ICMP_125 | ICMP_124 | Sulfate adenylyltransferase subunit 2. | Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.999 |
| cysD | cysQ | ICMP_125 | ICMP_169 | Sulfate adenylyltransferase subunit 2. | PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. | 0.952 |
| cysG | cysC | ICMP_126 | ICMP_123 | Uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.989 |
| cysG | cysD | ICMP_126 | ICMP_125 | Uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Sulfate adenylyltransferase subunit 2. | 0.984 |