| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cca | ftsQ | ICMP_571 | ICMP_392 | Fused tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase and phosphatase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 2 subfamily. | Membrane anchored protein; Involved in growth of wall at septum. | 0.529 |
| cca | holA | ICMP_571 | ICMP_504 | Fused tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase and phosphatase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 2 subfamily. | DNA polymerase III subunit delta. | 0.446 |
| cca | sspB | ICMP_571 | ICMP_160 | Fused tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase and phosphatase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 2 subfamily. | ClpXP protease specificity-enhancing factor. | 0.559 |
| cca | yggX | ICMP_571 | ICMP_566 | Fused tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase and phosphatase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 2 subfamily. | Hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | 0.553 |
| clpP | clpX | ICMP_344 | ICMP_343 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | ATP-dependent protease ATP-binding subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.999 |
| clpP | sspB | ICMP_344 | ICMP_160 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | ClpXP protease specificity-enhancing factor. | 0.771 |
| clpX | clpP | ICMP_343 | ICMP_344 | ATP-dependent protease ATP-binding subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.999 |
| clpX | sspB | ICMP_343 | ICMP_160 | ATP-dependent protease ATP-binding subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | ClpXP protease specificity-enhancing factor. | 0.914 |
| ftsQ | cca | ICMP_392 | ICMP_571 | Membrane anchored protein; Involved in growth of wall at septum. | Fused tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase and phosphatase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 2 subfamily. | 0.529 |
| ftsQ | holA | ICMP_392 | ICMP_504 | Membrane anchored protein; Involved in growth of wall at septum. | DNA polymerase III subunit delta. | 0.709 |
| ftsQ | rplM | ICMP_392 | ICMP_162 | Membrane anchored protein; Involved in growth of wall at septum. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.581 |
| ftsQ | rpsI | ICMP_392 | ICMP_161 | Membrane anchored protein; Involved in growth of wall at septum. | 30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. | 0.581 |
| ftsQ | sspB | ICMP_392 | ICMP_160 | Membrane anchored protein; Involved in growth of wall at septum. | ClpXP protease specificity-enhancing factor. | 0.647 |
| ftsQ | yggX | ICMP_392 | ICMP_566 | Membrane anchored protein; Involved in growth of wall at septum. | Hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | 0.468 |
| hisS | sspB | ICMP_072 | ICMP_160 | histidyl-tRNA synthetase. | ClpXP protease specificity-enhancing factor. | 0.480 |
| holA | cca | ICMP_504 | ICMP_571 | DNA polymerase III subunit delta. | Fused tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase and phosphatase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 2 subfamily. | 0.446 |
| holA | ftsQ | ICMP_504 | ICMP_392 | DNA polymerase III subunit delta. | Membrane anchored protein; Involved in growth of wall at septum. | 0.709 |
| holA | rnt | ICMP_504 | ICMP_438 | DNA polymerase III subunit delta. | Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. | 0.560 |
| holA | sspB | ICMP_504 | ICMP_160 | DNA polymerase III subunit delta. | ClpXP protease specificity-enhancing factor. | 0.653 |
| holA | yggX | ICMP_504 | ICMP_566 | DNA polymerase III subunit delta. | Hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | 0.432 |