| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| accA | accD | ICMP_194 | ICMP_042 | acetyl-CoA carboxylase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | acetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. | 0.999 |
| accA | birA | ICMP_194 | ICMP_537 | acetyl-CoA carboxylase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | Biotin--protein ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.455 |
| accA | dnaE | ICMP_194 | ICMP_195 | acetyl-CoA carboxylase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | DNA polymerase III subunit alpha. | 0.793 |
| accA | fabB | ICMP_194 | ICMP_099 | acetyl-CoA carboxylase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | 3-oxoacyl-(acyl carrier protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | 0.726 |
| accA | fabD | ICMP_194 | ICMP_371 | acetyl-CoA carboxylase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | Acyl carrier protein S-malonyltransferase. | 0.953 |
| accA | fabZ | ICMP_194 | ICMP_197 | acetyl-CoA carboxylase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | (3R)-hydroxymyristoyl ACP dehydratase. | 0.751 |
| accA | fabZ-2 | ICMP_194 | ICMP_198 | acetyl-CoA carboxylase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | (3R)-hydroxymyristoyl ACP dehydratase. | 0.751 |
| accA | rnhB | ICMP_194 | ICMP_196 | acetyl-CoA carboxylase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.670 |
| accA | yaeT | ICMP_194 | ICMP_199 | acetyl-CoA carboxylase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | Hypothetical protein. | 0.474 |
| accD | accA | ICMP_042 | ICMP_194 | acetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. | acetyl-CoA carboxylase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | 0.999 |
| accD | birA | ICMP_042 | ICMP_537 | acetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. | Biotin--protein ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.682 |
| accD | fabB | ICMP_042 | ICMP_099 | acetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. | 3-oxoacyl-(acyl carrier protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | 0.848 |
| accD | fabD | ICMP_042 | ICMP_371 | acetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. | Acyl carrier protein S-malonyltransferase. | 0.982 |
| accD | fabZ | ICMP_042 | ICMP_197 | acetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. | (3R)-hydroxymyristoyl ACP dehydratase. | 0.565 |
| accD | fabZ-2 | ICMP_042 | ICMP_198 | acetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. | (3R)-hydroxymyristoyl ACP dehydratase. | 0.565 |
| acpP | birA | ICMP_369 | ICMP_537 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | Biotin--protein ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.644 |
| acpP | fabB | ICMP_369 | ICMP_099 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | 3-oxoacyl-(acyl carrier protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | 0.969 |
| acpP | fabD | ICMP_369 | ICMP_371 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | Acyl carrier protein S-malonyltransferase. | 0.998 |
| acpP | fabZ | ICMP_369 | ICMP_197 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | (3R)-hydroxymyristoyl ACP dehydratase. | 0.839 |
| acpP | fabZ-2 | ICMP_369 | ICMP_198 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | (3R)-hydroxymyristoyl ACP dehydratase. | 0.839 |