| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ICMP_215 | amiB | ICMP_215 | ICMP_179 | Hypothetical protein; N-terminal transmembrane region have sequence similarity to sppA. | N-acetylmuramoyl-l-alanine amidase II. | 0.797 |
| ICMP_215 | folC | ICMP_215 | ICMP_043 | Hypothetical protein; N-terminal transmembrane region have sequence similarity to sppA. | Bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10- formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives. | 0.594 |
| ICMP_215 | ftsA | ICMP_215 | ICMP_391 | Hypothetical protein; N-terminal transmembrane region have sequence similarity to sppA. | Cell division protein; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | 0.900 |
| ICMP_215 | ftsI | ICMP_215 | ICMP_401 | Hypothetical protein; N-terminal transmembrane region have sequence similarity to sppA. | Transpeptidase; Involved in septal peptidoglycan synthesis. | 0.619 |
| ICMP_215 | ftsQ | ICMP_215 | ICMP_392 | Hypothetical protein; N-terminal transmembrane region have sequence similarity to sppA. | Membrane anchored protein; Involved in growth of wall at septum. | 0.630 |
| ICMP_215 | ftsW | ICMP_215 | ICMP_396 | Hypothetical protein; N-terminal transmembrane region have sequence similarity to sppA. | Integral membrane protein; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.692 |
| ICMP_215 | ftsZ | ICMP_215 | ICMP_390 | Hypothetical protein; N-terminal transmembrane region have sequence similarity to sppA. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.606 |
| ICMP_215 | mrdA | ICMP_215 | ICMP_506 | Hypothetical protein; N-terminal transmembrane region have sequence similarity to sppA. | Transpeptidase; Penicillin-binding protein 2. | 0.619 |
| ICMP_215 | mrdB | ICMP_215 | ICMP_507 | Hypothetical protein; N-terminal transmembrane region have sequence similarity to sppA. | Cell wall shape-determining protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.692 |
| ICMP_215 | xthA | ICMP_215 | ICMP_214 | Hypothetical protein; N-terminal transmembrane region have sequence similarity to sppA. | Exonuclease III. | 0.600 |
| amiB | ICMP_215 | ICMP_179 | ICMP_215 | N-acetylmuramoyl-l-alanine amidase II. | Hypothetical protein; N-terminal transmembrane region have sequence similarity to sppA. | 0.797 |
| amiB | ftsA | ICMP_179 | ICMP_391 | N-acetylmuramoyl-l-alanine amidase II. | Cell division protein; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | 0.682 |
| amiB | ftsI | ICMP_179 | ICMP_401 | N-acetylmuramoyl-l-alanine amidase II. | Transpeptidase; Involved in septal peptidoglycan synthesis. | 0.678 |
| amiB | ftsQ | ICMP_179 | ICMP_392 | N-acetylmuramoyl-l-alanine amidase II. | Membrane anchored protein; Involved in growth of wall at septum. | 0.443 |
| amiB | ftsW | ICMP_179 | ICMP_396 | N-acetylmuramoyl-l-alanine amidase II. | Integral membrane protein; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.669 |
| amiB | ftsZ | ICMP_179 | ICMP_390 | N-acetylmuramoyl-l-alanine amidase II. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.667 |
| amiB | mrdA | ICMP_179 | ICMP_506 | N-acetylmuramoyl-l-alanine amidase II. | Transpeptidase; Penicillin-binding protein 2. | 0.668 |
| amiB | mrdB | ICMP_179 | ICMP_507 | N-acetylmuramoyl-l-alanine amidase II. | Cell wall shape-determining protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.657 |
| amiB | xthA | ICMP_179 | ICMP_214 | N-acetylmuramoyl-l-alanine amidase II. | Exonuclease III. | 0.434 |
| folC | ICMP_215 | ICMP_043 | ICMP_215 | Bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10- formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives. | Hypothetical protein; N-terminal transmembrane region have sequence similarity to sppA. | 0.594 |