| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ftsZ | minC | ICMP_390 | ICMP_221 | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Septum formation inhibitor; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | 0.834 |
| ftsZ | minD | ICMP_390 | ICMP_222 | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Membrane ATPase of the MinC-MinD-MinE system. | 0.403 |
| ftsZ | mreB | ICMP_390 | ICMP_188 | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Cell wall structural complex MreBCD, actin-like component MreB. | 0.795 |
| ftsZ | mreC | ICMP_390 | ICMP_187 | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Cell wall structural complex MreBCD; Involved in formation and maintenance of cell shape. | 0.412 |
| minC | ftsZ | ICMP_221 | ICMP_390 | Septum formation inhibitor; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.834 |
| minC | minD | ICMP_221 | ICMP_222 | Septum formation inhibitor; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | Membrane ATPase of the MinC-MinD-MinE system. | 0.999 |
| minC | minE | ICMP_221 | ICMP_223 | Septum formation inhibitor; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | 0.923 |
| minC | mreB | ICMP_221 | ICMP_188 | Septum formation inhibitor; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | Cell wall structural complex MreBCD, actin-like component MreB. | 0.472 |
| minC | mreC | ICMP_221 | ICMP_187 | Septum formation inhibitor; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | Cell wall structural complex MreBCD; Involved in formation and maintenance of cell shape. | 0.826 |
| minC | mreD | ICMP_221 | ICMP_186 | Septum formation inhibitor; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | Cell wall structural complex MreBCD; Transmembrane component MreD. | 0.810 |
| minD | ftsZ | ICMP_222 | ICMP_390 | Membrane ATPase of the MinC-MinD-MinE system. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.403 |
| minD | minC | ICMP_222 | ICMP_221 | Membrane ATPase of the MinC-MinD-MinE system. | Septum formation inhibitor; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | 0.999 |
| minD | minE | ICMP_222 | ICMP_223 | Membrane ATPase of the MinC-MinD-MinE system. | Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | 0.996 |
| minD | mreB | ICMP_222 | ICMP_188 | Membrane ATPase of the MinC-MinD-MinE system. | Cell wall structural complex MreBCD, actin-like component MreB. | 0.506 |
| minD | mreC | ICMP_222 | ICMP_187 | Membrane ATPase of the MinC-MinD-MinE system. | Cell wall structural complex MreBCD; Involved in formation and maintenance of cell shape. | 0.718 |
| minD | mreD | ICMP_222 | ICMP_186 | Membrane ATPase of the MinC-MinD-MinE system. | Cell wall structural complex MreBCD; Transmembrane component MreD. | 0.632 |
| minE | minC | ICMP_223 | ICMP_221 | Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | Septum formation inhibitor; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | 0.923 |
| minE | minD | ICMP_223 | ICMP_222 | Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | Membrane ATPase of the MinC-MinD-MinE system. | 0.996 |
| mreB | ftsZ | ICMP_188 | ICMP_390 | Cell wall structural complex MreBCD, actin-like component MreB. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.795 |
| mreB | minC | ICMP_188 | ICMP_221 | Cell wall structural complex MreBCD, actin-like component MreB. | Septum formation inhibitor; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | 0.472 |