| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cysG | moaE | ICMP_126 | ICMP_473 | Uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Molybdopterin synthase large subunit. | 0.606 |
| cysG | moeB | ICMP_126 | ICMP_331 | Uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Molybdopterin biosynthesis protein MoeB. | 0.574 |
| cysG | thrA | ICMP_126 | ICMP_307 | Uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Bifunctional aspartokinase I/homeserine dehydrogenase I; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.580 |
| cysG | trxB | ICMP_126 | ICMP_325 | Uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Thioredoxin reductase, FAD/NAD(P)-binding. | 0.630 |
| dacC | moeA | ICMP_329 | ICMP_330 | D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. | Molybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | 0.552 |
| dacC | moeB | ICMP_329 | ICMP_331 | D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. | Molybdopterin biosynthesis protein MoeB. | 0.552 |
| hisI | moeB | ICMP_469 | ICMP_331 | Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; In the N-terminal section; belongs to the PRA-CH family. | Molybdopterin biosynthesis protein MoeB. | 0.569 |
| hisI | thrA | ICMP_469 | ICMP_307 | Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; In the N-terminal section; belongs to the PRA-CH family. | Bifunctional aspartokinase I/homeserine dehydrogenase I; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.840 |
| iscS | moeB | ICMP_069 | ICMP_331 | Cysteine desulfurase. | Molybdopterin biosynthesis protein MoeB. | 0.995 |
| iscS | thrA | ICMP_069 | ICMP_307 | Cysteine desulfurase. | Bifunctional aspartokinase I/homeserine dehydrogenase I; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.565 |
| moaD | moaE | ICMP_474 | ICMP_473 | Molybdopterin synthase small subunit. | Molybdopterin synthase large subunit. | 0.999 |
| moaD | moeA | ICMP_474 | ICMP_330 | Molybdopterin synthase small subunit. | Molybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | 0.709 |
| moaD | moeB | ICMP_474 | ICMP_331 | Molybdopterin synthase small subunit. | Molybdopterin biosynthesis protein MoeB. | 0.992 |
| moaD | thrA | ICMP_474 | ICMP_307 | Molybdopterin synthase small subunit. | Bifunctional aspartokinase I/homeserine dehydrogenase I; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.518 |
| moaE | cysG | ICMP_473 | ICMP_126 | Molybdopterin synthase large subunit. | Uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.606 |
| moaE | moaD | ICMP_473 | ICMP_474 | Molybdopterin synthase large subunit. | Molybdopterin synthase small subunit. | 0.999 |
| moaE | moeA | ICMP_473 | ICMP_330 | Molybdopterin synthase large subunit. | Molybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | 0.911 |
| moaE | moeB | ICMP_473 | ICMP_331 | Molybdopterin synthase large subunit. | Molybdopterin biosynthesis protein MoeB. | 0.885 |
| moaE | trxB | ICMP_473 | ICMP_325 | Molybdopterin synthase large subunit. | Thioredoxin reductase, FAD/NAD(P)-binding. | 0.401 |
| moeA | dacC | ICMP_330 | ICMP_329 | Molybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. | 0.552 |