| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ftsL | ftsN | ICMP_402 | ICMP_602 | Membrane bound cell division protein at septum containing leucine zipper motif. | Essential cell division protein. | 0.873 |
| ftsL | nlpB | ICMP_402 | ICMP_080 | Membrane bound cell division protein at septum containing leucine zipper motif. | Lipoprotein. | 0.769 |
| ftsL | secA | ICMP_402 | ICMP_389 | Membrane bound cell division protein at septum containing leucine zipper motif. | Translocase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. | 0.477 |
| ftsL | tsgA | ICMP_402 | ICMP_242 | Membrane bound cell division protein at septum containing leucine zipper motif. | Hypothetical protein. | 0.755 |
| ftsL | yacG | ICMP_402 | ICMP_388 | Membrane bound cell division protein at septum containing leucine zipper motif. | Zinc-finger protein. | 0.412 |
| ftsL | yfgM | ICMP_402 | ICMP_073 | Membrane bound cell division protein at septum containing leucine zipper motif. | Hypothetical protein. | 0.598 |
| ftsL | yqjE | ICMP_402 | ICMP_581 | Membrane bound cell division protein at septum containing leucine zipper motif. | Conserved inner membrane protein. | 0.724 |
| ftsN | ftsL | ICMP_602 | ICMP_402 | Essential cell division protein. | Membrane bound cell division protein at septum containing leucine zipper motif. | 0.873 |
| ftsN | nlpB | ICMP_602 | ICMP_080 | Essential cell division protein. | Lipoprotein. | 0.776 |
| ftsN | tsgA | ICMP_602 | ICMP_242 | Essential cell division protein. | Hypothetical protein. | 0.774 |
| ftsN | yacG | ICMP_602 | ICMP_388 | Essential cell division protein. | Zinc-finger protein. | 0.558 |
| ftsN | yfgM | ICMP_602 | ICMP_073 | Essential cell division protein. | Hypothetical protein. | 0.663 |
| ftsN | yqjE | ICMP_602 | ICMP_581 | Essential cell division protein. | Conserved inner membrane protein. | 0.774 |
| gyrA | gyrB | ICMP_065 | ICMP_017 | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.998 |
| gyrA | secA | ICMP_065 | ICMP_389 | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Translocase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. | 0.525 |
| gyrA | yacG | ICMP_065 | ICMP_388 | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Zinc-finger protein. | 0.538 |
| gyrB | gyrA | ICMP_017 | ICMP_065 | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.998 |
| gyrB | secA | ICMP_017 | ICMP_389 | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Translocase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. | 0.482 |
| gyrB | yacG | ICMP_017 | ICMP_388 | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Zinc-finger protein. | 0.535 |
| nlpB | ftsL | ICMP_080 | ICMP_402 | Lipoprotein. | Membrane bound cell division protein at septum containing leucine zipper motif. | 0.769 |