STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fumCFumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (478 aa)    
Predicted Functional Partners:
sdhA
Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
 
 0.996
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
  
 0.986
gltA
Citrate synthase; Belongs to the citrate synthase family.
   
 0.981
acnA
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
 0.959
sdhB
Succinate dehydrogenase FeS subunit.
  
 0.956
sfcA
Malate dehydrogenase.
  
 
 0.954
sdhC
Succinate dehydrogenase cytochrome b556 large membrane subunit.
   
 
 0.941
sdhD
Succinate dehydrogenase cytochrome b556 small membrane subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH).
   
 
 0.922
aspC
Aspartate aminotransferase.
   
 0.882
sucA
Alpha-ketoglutarate decarboxylase.
  
 
 0.838
Your Current Organism:
Ishikawaella capsulata
NCBI taxonomy Id: 476281
Other names: C. Ishikawaella capsulata Mpkobe, Candidatus Ishikawaella capsulata Mpkobe
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