node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
amiB | sufS | ICMP_179 | ICMP_444 | N-acetylmuramoyl-l-alanine amidase II. | Selenocysteine lyase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo. | 0.424 |
gntY | sufA | ICMP_115 | ICMP_448 | Predicted gluconate transport associated protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | Iron-sulfur cluster assembly scaffold protein; Belongs to the HesB/IscA family. | 0.536 |
gntY | sufB | ICMP_115 | ICMP_447 | Predicted gluconate transport associated protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | Component of SufBCD complex. | 0.744 |
gntY | sufC | ICMP_115 | ICMP_446 | Predicted gluconate transport associated protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | Cysteine desulfurase ATPase component. | 0.764 |
gntY | sufD | ICMP_115 | ICMP_445 | Predicted gluconate transport associated protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | Component of SufBCD complex. | 0.744 |
gntY | sufE | ICMP_115 | ICMP_443 | Predicted gluconate transport associated protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | Cysteine desufuration protein SufE. | 0.470 |
gntY | sufS | ICMP_115 | ICMP_444 | Predicted gluconate transport associated protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | Selenocysteine lyase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo. | 0.582 |
gntY | trxB | ICMP_115 | ICMP_325 | Predicted gluconate transport associated protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | Thioredoxin reductase, FAD/NAD(P)-binding. | 0.574 |
metB | sufS | ICMP_599 | ICMP_444 | Cystathionine gamma-synthase. | Selenocysteine lyase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo. | 0.900 |
sufA | gntY | ICMP_448 | ICMP_115 | Iron-sulfur cluster assembly scaffold protein; Belongs to the HesB/IscA family. | Predicted gluconate transport associated protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.536 |
sufA | sufB | ICMP_448 | ICMP_447 | Iron-sulfur cluster assembly scaffold protein; Belongs to the HesB/IscA family. | Component of SufBCD complex. | 0.971 |
sufA | sufC | ICMP_448 | ICMP_446 | Iron-sulfur cluster assembly scaffold protein; Belongs to the HesB/IscA family. | Cysteine desulfurase ATPase component. | 0.953 |
sufA | sufD | ICMP_448 | ICMP_445 | Iron-sulfur cluster assembly scaffold protein; Belongs to the HesB/IscA family. | Component of SufBCD complex. | 0.941 |
sufA | sufE | ICMP_448 | ICMP_443 | Iron-sulfur cluster assembly scaffold protein; Belongs to the HesB/IscA family. | Cysteine desufuration protein SufE. | 0.798 |
sufA | sufS | ICMP_448 | ICMP_444 | Iron-sulfur cluster assembly scaffold protein; Belongs to the HesB/IscA family. | Selenocysteine lyase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo. | 0.885 |
sufB | gntY | ICMP_447 | ICMP_115 | Component of SufBCD complex. | Predicted gluconate transport associated protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.744 |
sufB | sufA | ICMP_447 | ICMP_448 | Component of SufBCD complex. | Iron-sulfur cluster assembly scaffold protein; Belongs to the HesB/IscA family. | 0.971 |
sufB | sufC | ICMP_447 | ICMP_446 | Component of SufBCD complex. | Cysteine desulfurase ATPase component. | 0.999 |
sufB | sufD | ICMP_447 | ICMP_445 | Component of SufBCD complex. | Component of SufBCD complex. | 0.998 |
sufB | sufE | ICMP_447 | ICMP_443 | Component of SufBCD complex. | Cysteine desufuration protein SufE. | 0.943 |