STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mrdATranspeptidase; Penicillin-binding protein 2. (584 aa)    
Predicted Functional Partners:
mrdB
Cell wall shape-determining protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
 
 0.994
ftsI
Transpeptidase; Involved in septal peptidoglycan synthesis.
  
  
0.934
ftsW
Integral membrane protein; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.
 
 0.918
mreB
Cell wall structural complex MreBCD, actin-like component MreB.
 
 
 
 0.872
mreC
Cell wall structural complex MreBCD; Involved in formation and maintenance of cell shape.
 
 
 0.839
ftsQ
Membrane anchored protein; Involved in growth of wall at septum.
  
 
 0.808
amiB
N-acetylmuramoyl-l-alanine amidase II.
 
 
 0.706
ICMP_215
Hypothetical protein; N-terminal transmembrane region have sequence similarity to sppA.
  
 
 0.689
ftsL
Membrane bound cell division protein at septum containing leucine zipper motif.
 
 
 0.632
murE
UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
 
  
 0.606
Your Current Organism:
Ishikawaella capsulata
NCBI taxonomy Id: 476281
Other names: C. Ishikawaella capsulata Mpkobe, Candidatus Ishikawaella capsulata Mpkobe
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