| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cca | ftsQ | ICMP_571 | ICMP_392 | Fused tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase and phosphatase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 2 subfamily. | Membrane anchored protein; Involved in growth of wall at septum. | 0.529 |
| cca | holA | ICMP_571 | ICMP_504 | Fused tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase and phosphatase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 2 subfamily. | DNA polymerase III subunit delta. | 0.446 |
| cca | sspB | ICMP_571 | ICMP_160 | Fused tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase and phosphatase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 2 subfamily. | ClpXP protease specificity-enhancing factor. | 0.559 |
| cca | yggX | ICMP_571 | ICMP_566 | Fused tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase and phosphatase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 2 subfamily. | Hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | 0.553 |
| ftsQ | cca | ICMP_392 | ICMP_571 | Membrane anchored protein; Involved in growth of wall at septum. | Fused tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase and phosphatase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 2 subfamily. | 0.529 |
| ftsQ | hemD | ICMP_392 | ICMP_632 | Membrane anchored protein; Involved in growth of wall at septum. | uroporphyrinogen-III synthetase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.558 |
| ftsQ | holA | ICMP_392 | ICMP_504 | Membrane anchored protein; Involved in growth of wall at septum. | DNA polymerase III subunit delta. | 0.709 |
| ftsQ | sspB | ICMP_392 | ICMP_160 | Membrane anchored protein; Involved in growth of wall at septum. | ClpXP protease specificity-enhancing factor. | 0.647 |
| ftsQ | ygfZ | ICMP_392 | ICMP_143 | Membrane anchored protein; Involved in growth of wall at septum. | Putative global regulator; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family. | 0.435 |
| ftsQ | yggX | ICMP_392 | ICMP_566 | Membrane anchored protein; Involved in growth of wall at septum. | Hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | 0.468 |
| hemD | ftsQ | ICMP_632 | ICMP_392 | uroporphyrinogen-III synthetase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Membrane anchored protein; Involved in growth of wall at septum. | 0.558 |
| hemD | holA | ICMP_632 | ICMP_504 | uroporphyrinogen-III synthetase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | DNA polymerase III subunit delta. | 0.768 |
| hemD | ygfZ | ICMP_632 | ICMP_143 | uroporphyrinogen-III synthetase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Putative global regulator; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family. | 0.674 |
| hemD | yggX | ICMP_632 | ICMP_566 | uroporphyrinogen-III synthetase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | 0.425 |
| holA | cca | ICMP_504 | ICMP_571 | DNA polymerase III subunit delta. | Fused tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase and phosphatase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 2 subfamily. | 0.446 |
| holA | ftsQ | ICMP_504 | ICMP_392 | DNA polymerase III subunit delta. | Membrane anchored protein; Involved in growth of wall at septum. | 0.709 |
| holA | hemD | ICMP_504 | ICMP_632 | DNA polymerase III subunit delta. | uroporphyrinogen-III synthetase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.768 |
| holA | sspB | ICMP_504 | ICMP_160 | DNA polymerase III subunit delta. | ClpXP protease specificity-enhancing factor. | 0.653 |
| holA | ygfZ | ICMP_504 | ICMP_143 | DNA polymerase III subunit delta. | Putative global regulator; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family. | 0.535 |
| holA | yggX | ICMP_504 | ICMP_566 | DNA polymerase III subunit delta. | Hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | 0.432 |