| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aroB | thrA | ICMP_640 | ICMP_307 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | Bifunctional aspartokinase I/homeserine dehydrogenase I; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.651 |
| aroB | ygjD | ICMP_640 | ICMP_573 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.596 |
| dnaG | pheT | ICMP_575 | ICMP_416 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.706 |
| dnaG | polA | ICMP_575 | ICMP_658 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | DNA polymerase I. | 0.700 |
| dnaG | polA-2 | ICMP_575 | ICMP_659 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | DNA polymerase I. | 0.749 |
| dnaG | rpsU | ICMP_575 | ICMP_574 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 30S ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family. | 0.669 |
| dnaG | ygjD | ICMP_575 | ICMP_573 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.552 |
| folB | rpsU | ICMP_572 | ICMP_574 | Bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 30S ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family. | 0.415 |
| folB | ygjD | ICMP_572 | ICMP_573 | Bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.553 |
| guaA | pheT | ICMP_077 | ICMP_416 | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.922 |
| guaA | polA | ICMP_077 | ICMP_658 | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | DNA polymerase I. | 0.719 |
| guaA | polA-2 | ICMP_077 | ICMP_659 | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | DNA polymerase I. | 0.719 |
| guaA | thrA | ICMP_077 | ICMP_307 | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | Bifunctional aspartokinase I/homeserine dehydrogenase I; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.610 |
| guaA | yeaZ | ICMP_077 | ICMP_224 | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | Predicted peptidase. | 0.526 |
| guaA | ygjD | ICMP_077 | ICMP_573 | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.573 |
| pheT | dnaG | ICMP_416 | ICMP_575 | phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.706 |
| pheT | guaA | ICMP_416 | ICMP_077 | phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | 0.922 |
| pheT | polA | ICMP_416 | ICMP_658 | phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | DNA polymerase I. | 0.748 |
| pheT | polA-2 | ICMP_416 | ICMP_659 | phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | DNA polymerase I. | 0.709 |
| pheT | thrA | ICMP_416 | ICMP_307 | phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | Bifunctional aspartokinase I/homeserine dehydrogenase I; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.679 |