KLU67807.1 protein (Desulfosporosinus acididurans)

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Known Interactions

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Predicted Interactions

gene neighborhood

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Score

KLU67807.1

Succinate dehydrogenase/fumarate reductase iron-sulfur subunit. (537 aa)

Predicted Functional Partners:

KLU67808.1

0.938

nifJ_1

0.810

nifJ_3

0.810

dsvA

0.795

dsvB

0.794

dsvC

0.793

nifJ_2

0.783

lutB_1

0.777

lutB_3

0.777

lutB_4

0.777

Your Current Organism:

Desulfosporosinus acididurans

NCBI taxonomy Id: 476652
Other names: D. acididurans, DSM 27692, Desulfosporosinus acididurans Sanchez-Andrea et al. 2015, Desulfosporosinus sp. D, Desulfosporosinus sp. E, Desulfosporosinus sp. M1, JCM 19471, strain M1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KLU67807.1	KLU67808.1	DEAC_c02130	DEAC_c02140	Succinate dehydrogenase/fumarate reductase iron-sulfur subunit.	Hypothetical protein.	0.938
KLU67807.1	dsvA	DEAC_c02130	DEAC_c02110	Succinate dehydrogenase/fumarate reductase iron-sulfur subunit.	Sulfite reductase, dissimilatory-type subunit alpha.	0.795
KLU67807.1	dsvB	DEAC_c02130	DEAC_c02100	Succinate dehydrogenase/fumarate reductase iron-sulfur subunit.	Sulfite reductase, dissimilatory-type subunit beta.	0.794
KLU67807.1	dsvC	DEAC_c02130	DEAC_c27330	Succinate dehydrogenase/fumarate reductase iron-sulfur subunit.	Sulfite reductase, dissimilatory-type subunit gamma.	0.793
KLU67807.1	lutB_1	DEAC_c02130	DEAC_c03830	Succinate dehydrogenase/fumarate reductase iron-sulfur subunit.	Lactate utilization protein B.	0.777
KLU67807.1	lutB_3	DEAC_c02130	DEAC_c42850	Succinate dehydrogenase/fumarate reductase iron-sulfur subunit.	Lactate utilization protein B.	0.777
KLU67807.1	lutB_4	DEAC_c02130	DEAC_c42860	Succinate dehydrogenase/fumarate reductase iron-sulfur subunit.	Lactate utilization protein B.	0.777
KLU67807.1	nifJ_1	DEAC_c02130	DEAC_c06530	Succinate dehydrogenase/fumarate reductase iron-sulfur subunit.	Pyruvate-flavodoxin oxidoreductase.	0.810
KLU67807.1	nifJ_2	DEAC_c02130	DEAC_c10950	Succinate dehydrogenase/fumarate reductase iron-sulfur subunit.	Pyruvate-flavodoxin oxidoreductase.	0.783
KLU67807.1	nifJ_3	DEAC_c02130	DEAC_c39740	Succinate dehydrogenase/fumarate reductase iron-sulfur subunit.	Pyruvate-flavodoxin oxidoreductase.	0.810
KLU67808.1	KLU67807.1	DEAC_c02140	DEAC_c02130	Hypothetical protein.	Succinate dehydrogenase/fumarate reductase iron-sulfur subunit.	0.938
KLU67808.1	dsvA	DEAC_c02140	DEAC_c02110	Hypothetical protein.	Sulfite reductase, dissimilatory-type subunit alpha.	0.713
KLU67808.1	dsvB	DEAC_c02140	DEAC_c02100	Hypothetical protein.	Sulfite reductase, dissimilatory-type subunit beta.	0.737
KLU67808.1	dsvC	DEAC_c02140	DEAC_c27330	Hypothetical protein.	Sulfite reductase, dissimilatory-type subunit gamma.	0.717
dsvA	KLU67807.1	DEAC_c02110	DEAC_c02130	Sulfite reductase, dissimilatory-type subunit alpha.	Succinate dehydrogenase/fumarate reductase iron-sulfur subunit.	0.795
dsvA	KLU67808.1	DEAC_c02110	DEAC_c02140	Sulfite reductase, dissimilatory-type subunit alpha.	Hypothetical protein.	0.713
dsvA	dsvB	DEAC_c02110	DEAC_c02100	Sulfite reductase, dissimilatory-type subunit alpha.	Sulfite reductase, dissimilatory-type subunit beta.	0.985
dsvA	dsvC	DEAC_c02110	DEAC_c27330	Sulfite reductase, dissimilatory-type subunit alpha.	Sulfite reductase, dissimilatory-type subunit gamma.	0.976
dsvA	nifJ_1	DEAC_c02110	DEAC_c06530	Sulfite reductase, dissimilatory-type subunit alpha.	Pyruvate-flavodoxin oxidoreductase.	0.878
dsvA	nifJ_2	DEAC_c02110	DEAC_c10950	Sulfite reductase, dissimilatory-type subunit alpha.	Pyruvate-flavodoxin oxidoreductase.	0.858

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

21

average node degree:

3.82

avg. local clustering coefficient:

0.643

expected number of edges:

14

PPI enrichment p-value:

0.0389

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019439

Aromatic compound catabolic process

8 of 56

1.57

2.65

7.00e-09

GO:0009056

Catabolic process

9 of 193

1.09

1.28

9.89e-07

GO:0042537

Benzene-containing compound metabolic process

3 of 10

1.89

1.25

0.0034

GO:0019619

3,4-dihydroxybenzoate catabolic process

2 of 3

2.24

0.82

0.0312

GO:0044282

Small molecule catabolic process

4 of 92

1.06

0.57

0.0371

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0051213

Dioxygenase activity

4 of 13

1.91

1.83

0.00016

GO:0005506

Iron ion binding

4 of 13

1.91

1.83

0.00016

GO:0008199

Ferric iron binding

2 of 3

2.24

0.97

0.0160

GO:0004497

Monooxygenase activity

3 of 20

1.59

0.95

0.0106

GO:0016702

Oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen

2 of 5

2.02

0.83

0.0278

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1699

Mixed, incl. Degradation of aromatic compounds, and Coenzyme A transferase

4 of 27

1.59

1.21

0.0022

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map01220

Degradation of aromatic compounds

5 of 30

1.64

2.02

1.07e-05

map00362

Benzoate degradation

5 of 31

1.62

2.0

1.07e-05

map00643

Styrene degradation

2 of 4

2.12

1.17

0.0061

map00361

Chlorocyclohexane and chlorobenzene degradation

2 of 5

2.02

1.13

0.0069

map00622

Xylene degradation

2 of 14

1.57

0.74

0.0321

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0223

Dioxygenase

3 of 8

1.99

1.47

0.0013

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00775

Dioxygenase

2 of 2

2.42

0.8

0.0349

PF00111

2Fe-2S iron-sulfur cluster binding domain

2 of 2

2.42

0.8

0.0349

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