Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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csrAHypothetical protein; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW. (83 aa)    
Predicted Functional Partners:
fliW
Flagellar assembly factor FliW; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
 
 
 0.998
flgL
Flagellar hook-associated protein 3.
 
  
 0.916
flgK
Flagellar hook-associated protein 1.
 
  
 0.881
hag
Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
 
  
 0.861
hfq
RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.
   
  
 0.858
fliN
Flagellar motor switch protein FliN.
 
   0.805
fliS_1
Flagellar protein FliS.
 
  
 0.788
fliF
Flagellar M-ring protein; The M ring may be actively involved in energy transduction. Belongs to the FliF family.
 
  
 0.775
KLU65878.1
Flagellar protein FlaG.
  
    0.772
KLU65887.1
Anti-sigma28 factor FlgM.
  
  
 0.769
Your Current Organism:
Desulfosporosinus acididurans
NCBI taxonomy Id: 476652
Other names: D. acididurans, DSM 27692, Desulfosporosinus acididurans Sanchez-Andrea et al. 2015, Desulfosporosinus sp. D, Desulfosporosinus sp. E, Desulfosporosinus sp. M1, JCM 19471, strain M1
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