Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
sigARNA polymerase sigma factor SigA; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (395 aa)    
Predicted Functional Partners:
dnaG_2
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
  
 0.995
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.970
rpoA_1
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.966
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.953
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
 
 0.913
KLU64269.1
Bacterial transcription activator, effector binding domain.
  
 
 0.825
whiA
Sporulation transcription regulator WhiA; Involved in cell division and chromosome segregation.
  
 
 
 0.754
tetD
Transposon Tn10 TetD protein.
    
 
 0.750
KLU63644.1
Hypothetical protein.
    
 
 0.750
carD_1
RNA polymerase-binding transcription factor CarD.
   
 
 0.727
Your Current Organism:
Desulfosporosinus acididurans
NCBI taxonomy Id: 476652
Other names: D. acididurans, DSM 27692, Desulfosporosinus acididurans Sanchez-Andrea et al. 2015, Desulfosporosinus sp. D, Desulfosporosinus sp. E, Desulfosporosinus sp. M1, JCM 19471, strain M1
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