STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
sucDsuccinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (298 aa)    
Predicted Functional Partners:
sucC
succinyl-CoA ligase [ADP-forming] subunit beta.
 0.999
gltA_1
Citrate synthase; Belongs to the citrate synthase family.
 
 0.954
nifJ_2
Pyruvate-flavodoxin oxidoreductase.
  
 0.953
KLU65198.1
Adenylylsulfate reductase subunit alpha.
  
 0.932
KLU65205.1
Adenylylsulfate reductase subunit alpha.
  
 0.932
nifJ_1
Pyruvate-flavodoxin oxidoreductase.
  
 
 0.931
nifJ_3
Pyruvate-flavodoxin oxidoreductase.
  
 
 0.931
atpH
ATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
  
 
 0.929
gltB_2
Ferredoxin-dependent glutamate synthase 1.
  
 
 0.917
cfiA
2-oxoglutarate carboxylase large subunit.
  
 
 0.906
Your Current Organism:
Desulfosporosinus acididurans
NCBI taxonomy Id: 476652
Other names: D. acididurans, DSM 27692, Desulfosporosinus acididurans Sanchez-Andrea et al. 2015, Desulfosporosinus sp. D, Desulfosporosinus sp. E, Desulfosporosinus sp. M1, JCM 19471, strain M1
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