Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fdhF_1Formate dehydrogenase H; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (556 aa)    
Predicted Functional Partners:
fdhF_2
Formate dehydrogenase H.
     0.990
hndC_2
NADP-reducing hydrogenase subunit HndC.
  
 0.987
hndC_4
NADP-reducing hydrogenase subunit HndC.
  
 0.987
hndC_1
NADP-reducing hydrogenase subunit HndC.
  
 0.984
fdhA
Formate dehydrogenase subunit alpha precursor.
  
 0.984
sfrA
NADPH-Fe(3+) oxidoreductase subunit alpha.
     0.974
hyfA_2
Hydrogenase-4 component A.
 0.955
hndD_4
NADP-reducing hydrogenase subunit HndC.
  
 0.955
hndD_1
NADP-reducing hydrogenase subunit HndC.
  
 0.950
hndD_3
NADP-reducing hydrogenase subunit HndC.
  
 0.950
Your Current Organism:
Desulfosporosinus acididurans
NCBI taxonomy Id: 476652
Other names: D. acididurans, DSM 27692, Desulfosporosinus acididurans Sanchez-Andrea et al. 2015, Desulfosporosinus sp. D, Desulfosporosinus sp. E, Desulfosporosinus sp. M1, JCM 19471, strain M1
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.