Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ureFUrease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. (226 aa)    
Predicted Functional Partners:
ureC
Urease subunit alpha.
 
 
 0.993
ureD
Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.992
ureB
Urease subunit beta; Belongs to the urease beta subunit family.
 
 
 0.981
ureA
Urease subunit gamma; Belongs to the urease gamma subunit family.
 
 
 0.979
ureG_1
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
 
 0.972
ureE
Urease accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
 
  
 0.972
hypB
Hydrogenase isoenzymes nickel incorporation protein HypB.
 
 
 0.775
ureG_2
Urease accessory protein UreG.
  
 
 0.704
lptB_2
Lipopolysaccharide export system ATP-binding protein LptB.
 
   
 0.668
livF_2
High-affinity branched-chain amino acid transport ATP-binding protein LivF.
 
   
 0.619
Your Current Organism:
Desulfosporosinus acididurans
NCBI taxonomy Id: 476652
Other names: D. acididurans, DSM 27692, Desulfosporosinus acididurans Sanchez-Andrea et al. 2015, Desulfosporosinus sp. D, Desulfosporosinus sp. E, Desulfosporosinus sp. M1, JCM 19471, strain M1
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