KLU64074.1 protein (Desulfosporosinus acididurans)

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second shell of interactors

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Edges:

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

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[Homology]

Score

KLU64074.1

acyl-CoA dehydrogenase, short-chain specific. (604 aa)

Predicted Functional Partners:

fadN

0.983

hndC_2

0.946

hndC_4

0.946

nifJ_2

0.910

acrA_3

0.862

echA8_1

0.844

nifJ_1

0.843

nifJ_3

0.843

fadA_2

0.839

acrA_1

0.837

Your Current Organism:

Desulfosporosinus acididurans

NCBI taxonomy Id: 476652
Other names: D. acididurans, DSM 27692, Desulfosporosinus acididurans Sanchez-Andrea et al. 2015, Desulfosporosinus sp. D, Desulfosporosinus sp. E, Desulfosporosinus sp. M1, JCM 19471, strain M1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KLU64074.1	acrA_1	DEAC_c40680	DEAC_c01550	acyl-CoA dehydrogenase, short-chain specific.	acryloyl-CoA reductase electron transfer subunit beta.	0.837
KLU64074.1	acrA_3	DEAC_c40680	DEAC_c27470	acyl-CoA dehydrogenase, short-chain specific.	acryloyl-CoA reductase electron transfer subunit beta.	0.862
KLU64074.1	echA8_1	DEAC_c40680	DEAC_c01330	acyl-CoA dehydrogenase, short-chain specific.	Putative enoyl-CoA hydratase echA8; Belongs to the enoyl-CoA hydratase/isomerase family.	0.844
KLU64074.1	fadA_2	DEAC_c40680	DEAC_c40660	acyl-CoA dehydrogenase, short-chain specific.	3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	0.839
KLU64074.1	fadN	DEAC_c40680	DEAC_c40670	acyl-CoA dehydrogenase, short-chain specific.	Putative 3-hydroxyacyl-CoA dehydrogenase.	0.983
KLU64074.1	hndC_2	DEAC_c40680	DEAC_c08640	acyl-CoA dehydrogenase, short-chain specific.	NADP-reducing hydrogenase subunit HndC.	0.946
KLU64074.1	hndC_4	DEAC_c40680	DEAC_c30960	acyl-CoA dehydrogenase, short-chain specific.	NADP-reducing hydrogenase subunit HndC.	0.946
KLU64074.1	nifJ_1	DEAC_c40680	DEAC_c06530	acyl-CoA dehydrogenase, short-chain specific.	Pyruvate-flavodoxin oxidoreductase.	0.843
KLU64074.1	nifJ_2	DEAC_c40680	DEAC_c10950	acyl-CoA dehydrogenase, short-chain specific.	Pyruvate-flavodoxin oxidoreductase.	0.910
KLU64074.1	nifJ_3	DEAC_c40680	DEAC_c39740	acyl-CoA dehydrogenase, short-chain specific.	Pyruvate-flavodoxin oxidoreductase.	0.843
acrA_1	KLU64074.1	DEAC_c01550	DEAC_c40680	acryloyl-CoA reductase electron transfer subunit beta.	acyl-CoA dehydrogenase, short-chain specific.	0.837
acrA_1	echA8_1	DEAC_c01550	DEAC_c01330	acryloyl-CoA reductase electron transfer subunit beta.	Putative enoyl-CoA hydratase echA8; Belongs to the enoyl-CoA hydratase/isomerase family.	0.647
acrA_1	fadA_2	DEAC_c01550	DEAC_c40660	acryloyl-CoA reductase electron transfer subunit beta.	3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	0.667
acrA_1	fadN	DEAC_c01550	DEAC_c40670	acryloyl-CoA reductase electron transfer subunit beta.	Putative 3-hydroxyacyl-CoA dehydrogenase.	0.872
acrA_1	hndC_2	DEAC_c01550	DEAC_c08640	acryloyl-CoA reductase electron transfer subunit beta.	NADP-reducing hydrogenase subunit HndC.	0.896
acrA_1	hndC_4	DEAC_c01550	DEAC_c30960	acryloyl-CoA reductase electron transfer subunit beta.	NADP-reducing hydrogenase subunit HndC.	0.896
acrA_1	nifJ_1	DEAC_c01550	DEAC_c06530	acryloyl-CoA reductase electron transfer subunit beta.	Pyruvate-flavodoxin oxidoreductase.	0.955
acrA_1	nifJ_2	DEAC_c01550	DEAC_c10950	acryloyl-CoA reductase electron transfer subunit beta.	Pyruvate-flavodoxin oxidoreductase.	0.981
acrA_1	nifJ_3	DEAC_c01550	DEAC_c39740	acryloyl-CoA reductase electron transfer subunit beta.	Pyruvate-flavodoxin oxidoreductase.	0.955
acrA_3	KLU64074.1	DEAC_c27470	DEAC_c40680	acryloyl-CoA reductase electron transfer subunit beta.	acyl-CoA dehydrogenase, short-chain specific.	0.862

page 1 of 5

Network Stats

number of nodes:

11

number of edges:

32

average node degree:

5.82

avg. local clustering coefficient:

0.882

expected number of edges:

11

PPI enrichment p-value:

1.46e-07

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0022900

Electron transport chain

5 of 55

1.4

1.17

0.0013

GO:0032259

Methylation

4 of 71

1.2

0.6

0.0402

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009055

Electron transfer activity

4 of 44

1.4

0.88

0.0102

GO:0008168

Methyltransferase activity

4 of 71

1.2

0.64

0.0304

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2428

Mixed, incl. Mitochondrion organization, and Methyltransferase domain

4 of 5

2.35

2.65

7.99e-06

CL:2395

Mostly uncharacterized, incl. Porphyrin and chlorophyll metabolism, and Methyltransferase domain

5 of 36

1.59

1.76

5.15e-05

CL:2079

Mixed, incl. NADH dehydrogenase activity, and Ubiquinol-cytochrome-c reductase activity

4 of 32

1.54

1.42

0.00044

CL:2098

Quinone

2 of 6

1.97

1.0

0.0122

CL:2123

Ubiquinol-cytochrome-c reductase activity, and Peptidase M16, C-terminal

2 of 10

1.75

0.8

0.0271

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0030425

Dendrite

2 of 2

2.44

0.93

0.0198

GOCC:0030424

Axon

2 of 2

2.44

0.93

0.0198

GOCC:0070469

Respirasome

3 of 30

1.44

0.79

0.0198

GOCC:0030964

NADH dehydrogenase complex

2 of 13

1.63

0.69

0.0423

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF13578

Methyltransferase domain

2 of 2

2.44

0.82

0.0317

PF00034

Cytochrome c

2 of 4

2.14

0.76

0.0394

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR002327

Cytochrome c, class IA/ IB

2 of 2

2.44

0.75

0.0431

IPR029063

S-adenosyl-L-methionine-dependent methyltransferase superfamily

4 of 48

1.37

0.71

0.0273

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