| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| OBX65011.1 | guaA | A9309_02785 | A9309_09270 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.725 |
| OBX65011.1 | guaB | A9309_02785 | A9309_03210 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.571 |
| OBX65011.1 | mnmC | A9309_02785 | A9309_02790 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Hypothetical protein; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. | 0.796 |
| OBX65011.1 | purB | A9309_02785 | A9309_07065 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.447 |
| OBX65011.1 | pyrF | A9309_02785 | A9309_07260 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.467 |
| OBX65011.1 | rdgB | A9309_02785 | A9309_04030 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.470 |
| OBX65011.1 | rnhB | A9309_02785 | A9309_02795 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Hypothetical protein; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.464 |
| OBX65011.1 | yciB | A9309_02785 | A9309_02775 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Septation protein IspZ; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family. | 0.559 |
| OBX65011.1 | yciI | A9309_02785 | A9309_02780 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.834 |
| guaA | OBX65011.1 | A9309_09270 | A9309_02785 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.725 |
| guaA | guaB | A9309_09270 | A9309_03210 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
| guaA | purB | A9309_09270 | A9309_07065 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.836 |
| guaA | pyrF | A9309_09270 | A9309_07260 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.834 |
| guaA | rdgB | A9309_09270 | A9309_04030 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.960 |
| guaB | OBX65011.1 | A9309_03210 | A9309_02785 | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.571 |
| guaB | guaA | A9309_03210 | A9309_09270 | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.999 |
| guaB | purB | A9309_03210 | A9309_07065 | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.816 |
| guaB | rdgB | A9309_03210 | A9309_04030 | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.942 |
| mnmC | OBX65011.1 | A9309_02790 | A9309_02785 | Hypothetical protein; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.796 |
| mnmC | rnhB | A9309_02790 | A9309_02795 | Hypothetical protein; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. | Hypothetical protein; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.514 |