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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mecAAdaptor protein MecA; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. (227 aa)    
Predicted Functional Partners:
clpB
ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
   
 
 0.838
AQG72306.1
ATP-dependent Clp protease ATP-binding subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family.
    
 
 0.826
AQG72493.1
ATP-dependent Clp protease ATP-binding subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family.
    
 
 0.826
clpC_2
ATP-dependent Clp protease ATP-binding subunit ClpC; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family.
    
 
 0.826
AQG72992.1
ATP-dependent Clp protease ATP-binding subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.826
AQG71479.1
Dihydroorotate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.807
spxA
Arsenate reductase; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily.
  
  
 0.749
pbpF_2
Carboxypeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.703
AQG72042.1
DNA replication protein DnaD; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.699
rpoE
DNA-directed RNA polymerase subunit delta; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family.
  
     0.685
Your Current Organism:
Lactobacillus rhamnosus
NCBI taxonomy Id: 47715
Other names: ATCC 7469, CCUG 21452, CIP A157, DSM 20021, IFO 3425, L. rhamnosus, LMG 6400, LMG:6400, Lactobacillus casei rhamnosus, Lactobacillus casei subsp. rhamnosus, Lactobacillus sp. NCIM 2587, Lactobacillus sp. W6, Lactobacillus sp. X9, NBRC 3425, NCAIM B.01147, NCCB 46033, NCDO 243, NCIB 6375, NCIMB 6375, NCTC 12953, NCTC 13764, NRRL B-442, VKM B-574
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