STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AQG73006.1Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology. (366 aa)    
Predicted Functional Partners:
AQG74165.1
Excisionase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.630
AQG71505.1
Competence protein ComF; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.554
AQG73299.1
Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 'phage' integrase family.
  
     0.539
AQG72938.1
Conjugal transfer protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.512
AQG73007.1
Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.509
whiA
Sporulation regulator WhiA; Involved in cell division and chromosome segregation.
   
    0.493
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.467
AQG72955.1
Conjugal transfer protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.455
eutD
Phosphotransacetylase; In Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.448
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
    
  0.420
Your Current Organism:
Lactobacillus rhamnosus
NCBI taxonomy Id: 47715
Other names: ATCC 7469, CCUG 21452, CIP A157, DSM 20021, IFO 3425, L. rhamnosus, LMG 6400, LMG:6400, Lactobacillus casei rhamnosus, Lactobacillus casei subsp. rhamnosus, Lactobacillus sp. NCIM 2587, Lactobacillus sp. W6, Lactobacillus sp. X9, NBRC 3425, NCAIM B.01147, NCCB 46033, NCDO 243, NCIB 6375, NCIMB 6375, NCTC 12953, NCTC 13764, NRRL B-442, VKM B-574
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.