STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KYC_04202Voltage gated chloride channel family protein 1; COG0038 Chloride channel protein EriC. (601 aa)    
Predicted Functional Partners:
KYC_04207
COG1846 Transcriptional regulators.
 
     0.882
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
  0.756
KYC_26142
Voltage gated chloride channel family protein 2; COG0038 Chloride channel protein EriC.
 
     0.726
atpB
F0F1 ATP synthase subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family.
    
 0.682
KYC_04212
Hypothetical protein; COG3448 CBS-domain-containing membrane protein.
    
  0.664
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.599
KYC_21861
Haloacid dehalogenase, type II; COG1011 Predicted hydrolase (HAD superfamily).
 
  
  0.596
atpE
F0F1 ATP synthase subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
    
 0.564
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
  0.554
KYC_23063
Arabinose 5-phosphate isomerase; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily.
    
  0.545
Your Current Organism:
Achromobacter arsenitoxydans
NCBI taxonomy Id: 477184
Other names: A. arsenitoxydans SY8, Achromobacter arsenitoxydans SY8, Achromobacter arsenitoxydans str. SY8, Achromobacter arsenitoxydans strain SY8, Achromobacter sp. SY8, arsenite-oxidizing bacterium SY8
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