STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KYC_045472',3'-cyclic-nucleotide 2'-phosphodiesterase; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. (705 aa)    
Predicted Functional Partners:
surE
5'(3')-nucleotidase/polyphosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.868
KYC_28242
Putative 5'(3')-deoxyribonucleotidase; COG4502 Uncharacterized protein conserved in bacteria.
     
 0.851
KYC_05396
COG0524 Sugar kinases, ribokinase family.
    
 0.819
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
 0.803
KYC_19624
Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.
    
 0.789
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.767
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
    
  0.755
KYC_07111
NADH pyrophosphatase; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding.
    
  0.750
KYC_08675
COG2857 Cytochrome c1.
 
  
 0.663
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
    
 0.606
Your Current Organism:
Achromobacter arsenitoxydans
NCBI taxonomy Id: 477184
Other names: A. arsenitoxydans SY8, Achromobacter arsenitoxydans SY8, Achromobacter arsenitoxydans str. SY8, Achromobacter arsenitoxydans strain SY8, Achromobacter sp. SY8, arsenite-oxidizing bacterium SY8
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