STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KYC_17868COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (509 aa)    
Predicted Functional Partners:
acsA
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
  0.967
KYC_17613
COG1062 Zn-dependent alcohol dehydrogenases, class III; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
 
  0.960
KYC_12977
COG1064 Zn-dependent alcohol dehydrogenases.
 
 
 
  0.956
KYC_10136
AMP-binding protein; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases.
   
  0.943
KYC_10838
AMP-binding protein; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases.
   
  0.943
ackA
Acetate kinase A/propionate kinase 2; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
  
 
 0.933
KYC_01000
COG0427 Acetyl-CoA hydrolase.
  
 
 0.925
KYC_00290
COG1254 Acylphosphatases.
     
 0.924
KYC_20454
Zinc-binding dehydrogenase family protein 6; COG1064 Zn-dependent alcohol dehydrogenases.
   
 
  0.924
KYC_20729
COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family.
   
 
  0.922
Your Current Organism:
Achromobacter arsenitoxydans
NCBI taxonomy Id: 477184
Other names: A. arsenitoxydans SY8, Achromobacter arsenitoxydans SY8, Achromobacter arsenitoxydans str. SY8, Achromobacter arsenitoxydans strain SY8, Achromobacter sp. SY8, arsenite-oxidizing bacterium SY8
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