node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KYC_18515 | KYC_18530 | KYC_18515 | KYC_18530 | Transmembrane protein 1; COG2976 Uncharacterized protein conserved in bacteria. | COG1426 Uncharacterized protein conserved in bacteria. | 0.730 |
KYC_18515 | bamB | KYC_18515 | KYC_18510 | Transmembrane protein 1; COG2976 Uncharacterized protein conserved in bacteria. | Outer membrane assembly lipoprotein YfgL; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.987 |
KYC_18515 | hisS | KYC_18515 | KYC_18520 | Transmembrane protein 1; COG2976 Uncharacterized protein conserved in bacteria. | COG0124 Histidyl-tRNA synthetase. | 0.983 |
KYC_18515 | ispG | KYC_18515 | KYC_18525 | Transmembrane protein 1; COG2976 Uncharacterized protein conserved in bacteria. | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.833 |
KYC_18515 | ndk | KYC_18515 | KYC_18540 | Transmembrane protein 1; COG2976 Uncharacterized protein conserved in bacteria. | Mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-phosphodiesterase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.695 |
KYC_18515 | rlmN | KYC_18515 | KYC_18535 | Transmembrane protein 1; COG2976 Uncharacterized protein conserved in bacteria. | Ribosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.797 |
KYC_18530 | KYC_18515 | KYC_18530 | KYC_18515 | COG1426 Uncharacterized protein conserved in bacteria. | Transmembrane protein 1; COG2976 Uncharacterized protein conserved in bacteria. | 0.730 |
KYC_18530 | bamB | KYC_18530 | KYC_18510 | COG1426 Uncharacterized protein conserved in bacteria. | Outer membrane assembly lipoprotein YfgL; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.679 |
KYC_18530 | hisS | KYC_18530 | KYC_18520 | COG1426 Uncharacterized protein conserved in bacteria. | COG0124 Histidyl-tRNA synthetase. | 0.769 |
KYC_18530 | ispG | KYC_18530 | KYC_18525 | COG1426 Uncharacterized protein conserved in bacteria. | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.939 |
KYC_18530 | ndk | KYC_18530 | KYC_18540 | COG1426 Uncharacterized protein conserved in bacteria. | Mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-phosphodiesterase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.716 |
KYC_18530 | rlmN | KYC_18530 | KYC_18535 | COG1426 Uncharacterized protein conserved in bacteria. | Ribosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.881 |
bamB | KYC_18515 | KYC_18510 | KYC_18515 | Outer membrane assembly lipoprotein YfgL; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Transmembrane protein 1; COG2976 Uncharacterized protein conserved in bacteria. | 0.987 |
bamB | KYC_18530 | KYC_18510 | KYC_18530 | Outer membrane assembly lipoprotein YfgL; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | COG1426 Uncharacterized protein conserved in bacteria. | 0.679 |
bamB | hisS | KYC_18510 | KYC_18520 | Outer membrane assembly lipoprotein YfgL; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | COG0124 Histidyl-tRNA synthetase. | 0.944 |
bamB | ispG | KYC_18510 | KYC_18525 | Outer membrane assembly lipoprotein YfgL; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.807 |
bamB | ndk | KYC_18510 | KYC_18540 | Outer membrane assembly lipoprotein YfgL; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-phosphodiesterase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.689 |
bamB | rlmN | KYC_18510 | KYC_18535 | Outer membrane assembly lipoprotein YfgL; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Ribosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.794 |
dxr | ispD | KYC_25348 | KYC_09125 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | 0.987 |
dxr | ispF | KYC_25348 | KYC_09130 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.921 |