Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
T261_1985Hypothetical protein. (237 aa)    
Predicted Functional Partners:
T261_6111
DNA polymerase III subunit alpha.
  
 0.989
T261_3763
Hypothetical protein.
  
 0.988
T261_4147
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.988
T261_5504
Hypothetical protein.
 
 
 0.988
T261_3846
DNA polymerase III subunit gamma/tau.
  
 0.987
T261_6317
Hypothetical protein.
  
  
  0.978
T261_6721
Hypothetical protein.
     
  0.975
T261_4105
Hypothetical protein.
   
 0.791
T261_6443
Hypothetical protein; Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
  
 0.752
T261_2861
ATP-dependent DNA helicase UvrD2.
  
 0.681
Your Current Organism:
Streptomyces lydicus
NCBI taxonomy Id: 47763
Other names: ATCC 25470, BCRC 11919, CBS 703.69, CCRC 11919, CCRC:11919, CECT 3163, DSM 40461, IFO 13058, IMET 43531, ISP 5461, JCM 4492, LMG 19331, LMG:19331, NBRC 13058, NCIMB 12977, NRRL 2433, NRRL-ISP 5461, S. lydicus
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