STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
carA-2Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. (392 aa)    
Predicted Functional Partners:
carB
Carbamoyl-phosphate synthase large chain; Belongs to the CarB family.
 
 0.999
T261_2137
Carbamoyl-phosphate synthase large chain.
 
 0.999
AQY20317.1
Hypothetical protein.
 
 0.998
pyrB
Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
 0.992
pyrC
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
  
 0.990
T261_1831
Allantoinase.
  
 0.978
pyrD
Dihydroorotate dehydrogenase (quinone); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
 
  
 0.916
pyrF
Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.
 
  
 0.911
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
 
  
 0.893
T261_8167
Hypothetical protein.
  
  
 0.873
Your Current Organism:
Streptomyces lydicus
NCBI taxonomy Id: 47763
Other names: ATCC 25470, BCRC 11919, CBS 703.69, CCRC 11919, CCRC:11919, CECT 3163, DSM 40461, IFO 13058, IMET 43531, ISP 5461, JCM 4492, LMG 19331, LMG:19331, NBRC 13058, NCIMB 12977, NRRL 2433, NRRL-ISP 5461, S. lydicus
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.