STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
T261_3208Hypothetical protein. (245 aa)    
Predicted Functional Partners:
T261_2995
Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
 0.903
T261_4615
2-oxoglutarate oxidoreductase subunit KorA.
    
  0.886
T261_2644
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
    
  0.883
accD
Acetyl-coenzyme A carboxylase carboxyl transferase subunits beta/alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
    
 0.803
T261_7250
Acetyl-coenzyme A carboxylase carboxyl transferase subunits beta/alpha.
    
 0.803
T261_3326
Putative citrate synthase 2; Belongs to the citrate synthase family.
  
 0.776
T261_5334
Citrate synthase 1; Belongs to the citrate synthase family.
  
 0.776
T261_1839
Malate synthase; Belongs to the malate synthase family.
  
 0.763
T261_1890
Pyruvate dehydrogenase; Belongs to the TPP enzyme family.
  
 
 0.748
T261_2052
Aconitate hydratase A; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
 
 0.677
Your Current Organism:
Streptomyces lydicus
NCBI taxonomy Id: 47763
Other names: ATCC 25470, BCRC 11919, CBS 703.69, CCRC 11919, CCRC:11919, CECT 3163, DSM 40461, IFO 13058, IMET 43531, ISP 5461, JCM 4492, LMG 19331, LMG:19331, NBRC 13058, NCIMB 12977, NRRL 2433, NRRL-ISP 5461, S. lydicus
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.