node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
T261_3618 | T261_3619 | T261_3618 | T261_3619 | Hypothetical protein. | Tryptophan--tRNA ligase 2; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.572 |
T261_3619 | T261_3618 | T261_3619 | T261_3618 | Tryptophan--tRNA ligase 2; Belongs to the class-I aminoacyl-tRNA synthetase family. | Hypothetical protein. | 0.572 |
T261_3619 | gltX | T261_3619 | T261_2504 | Tryptophan--tRNA ligase 2; Belongs to the class-I aminoacyl-tRNA synthetase family. | Glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | 0.565 |
T261_3619 | ileS | T261_3619 | T261_6096 | Tryptophan--tRNA ligase 2; Belongs to the class-I aminoacyl-tRNA synthetase family. | Isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | 0.734 |
T261_3619 | lepA | T261_3619 | T261_5506 | Tryptophan--tRNA ligase 2; Belongs to the class-I aminoacyl-tRNA synthetase family. | Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.658 |
T261_3619 | leuS | T261_3619 | T261_5495 | Tryptophan--tRNA ligase 2; Belongs to the class-I aminoacyl-tRNA synthetase family. | Leucine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.805 |
T261_3619 | pheT | T261_3619 | T261_6651 | Tryptophan--tRNA ligase 2; Belongs to the class-I aminoacyl-tRNA synthetase family. | Phenylalanine--tRNA ligase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.644 |
T261_3619 | prfA | T261_3619 | T261_2709 | Tryptophan--tRNA ligase 2; Belongs to the class-I aminoacyl-tRNA synthetase family. | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.606 |
T261_3619 | serS | T261_3619 | T261_4047 | Tryptophan--tRNA ligase 2; Belongs to the class-I aminoacyl-tRNA synthetase family. | Serine--tRNA ligase 1; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). | 0.788 |
T261_3619 | trpE | T261_3619 | T261_6137 | Tryptophan--tRNA ligase 2; Belongs to the class-I aminoacyl-tRNA synthetase family. | Anthranilate synthase component 1; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.607 |
T261_3619 | valS | T261_3619 | T261_5456 | Tryptophan--tRNA ligase 2; Belongs to the class-I aminoacyl-tRNA synthetase family. | Valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. | 0.575 |
gltX | T261_3619 | T261_2504 | T261_3619 | Glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | Tryptophan--tRNA ligase 2; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.565 |
gltX | ileS | T261_2504 | T261_6096 | Glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | Isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | 0.993 |
gltX | lepA | T261_2504 | T261_5506 | Glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.556 |
gltX | leuS | T261_2504 | T261_5495 | Glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | Leucine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.992 |
gltX | pheT | T261_2504 | T261_6651 | Glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | Phenylalanine--tRNA ligase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.924 |
gltX | prfA | T261_2504 | T261_2709 | Glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.666 |
gltX | serS | T261_2504 | T261_4047 | Glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | Serine--tRNA ligase 1; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). | 0.749 |
gltX | valS | T261_2504 | T261_5456 | Glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | Valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. | 0.749 |
ileS | T261_3619 | T261_6096 | T261_3619 | Isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | Tryptophan--tRNA ligase 2; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.734 |