Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (435 aa)    
Predicted Functional Partners:
kynA
Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
 
 
 0.999
katG
Catalase-peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.
    
  0.975
T261_4402
Hypothetical protein.
 
 
 0.935
T261_4755
Hypothetical protein.
  
 
 0.896
T261_7487
Hypothetical protein.
  
 
 0.896
T261_1855
Catalase; Belongs to the catalase family.
  
 
  0.737
T261_2837
Bromoperoxidase-catalase; Belongs to the catalase family.
  
 
  0.737
T261_3003
Catalase; Belongs to the catalase family.
  
 
  0.737
T261_5200
Nicotinate phosphoribosyltransferase pncB1; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
    
 
 0.624
T261_4398
Hypothetical protein; Belongs to the major facilitator superfamily.
  
    0.619
Your Current Organism:
Streptomyces lydicus
NCBI taxonomy Id: 47763
Other names: ATCC 25470, BCRC 11919, CBS 703.69, CCRC 11919, CCRC:11919, CECT 3163, DSM 40461, IFO 13058, IMET 43531, ISP 5461, JCM 4492, LMG 19331, LMG:19331, NBRC 13058, NCIMB 12977, NRRL 2433, NRRL-ISP 5461, S. lydicus
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