STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (182 aa)    
Predicted Functional Partners:
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.969
T261_6407
Putative prephenate dehydrogenase NovF.
  
  
 0.891
T261_5099
Hypothetical protein.
   
    0.881
T261_4875
Purine nucleoside phosphorylase; Purine nucleoside phosphorylase involved in purine salvage.
 
 0.876
whiB-5
Transcriptional regulator WhiB4; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
    0.855
T261_4227
Hypothetical protein.
  
    0.827
secD
Protein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
  
    0.804
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
  
 0.765
secF
Protein translocase subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
       0.751
T261_0561
Hypothetical protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 
 0.740
Your Current Organism:
Streptomyces lydicus
NCBI taxonomy Id: 47763
Other names: ATCC 25470, BCRC 11919, CBS 703.69, CCRC 11919, CCRC:11919, CECT 3163, DSM 40461, IFO 13058, IMET 43531, ISP 5461, JCM 4492, LMG 19331, LMG:19331, NBRC 13058, NCIMB 12977, NRRL 2433, NRRL-ISP 5461, S. lydicus
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