Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hyuAN-methylhydantoinase A/acetone carboxylase, beta subunit; Function of strongly homologous gene; enzyme. (689 aa)    
Predicted Functional Partners:
hyuB
N-methylhydantoinase B/acetone carboxylase, alpha subunit; Function of strongly homologous gene; enzyme.
 0.999
CCH89453.1
N-methylhydantoinase B/acetone carboxylase, alpha subunit; Function of strongly homologous gene; enzyme.
 0.998
gltB
Glutamate synthase [NADPH] large chain (NADPH-GOGAT); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 0.924
bar
Barbiturase; Responsible for the hydrolysis of barbituric acid (2,4,6- trihydroxy-1,3-pyrimidine), an intermediate in the oxidative catabolism of pyrimidines. Catalyzes the hydrolytic opening of the pyrimidine ring of barbituric acid to yield ureidomalonic acid; Belongs to the cyclic amide hydrolase (CyAH) family.
 
     0.786
cdd
Cytosine deaminase; Function of strongly homologous gene; enzyme.
     
  0.639
tadA
tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
     
  0.621
codA
Cytosine deaminase; Function of strongly homologous gene; enzyme.
     
  0.621
CCH88700.1
Putative cytosine deaminase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
  0.621
CCH85600.1
Homologs of previously reported genes of unknown function.
       0.551
CCH88704.1
Purine catabolism regulator-like protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; regulator.
 
     0.549
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
Server load: low (8%) [HD]