STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sucDSuccinyl-CoA synthetase, alpha subunit; Function of strongly homologous gene; enzyme. (490 aa)    
Predicted Functional Partners:
sucC
Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
 0.996
CCH85640.1
Homologs of previously reported genes of unknown function.
     0.995
sucA
2-oxoglutarate decarboxylase; Function of strongly homologous gene; enzyme.
  
 
 0.982
CCH88706.1
Homologs of previously reported genes of unknown function.
 
   0.803
arcC
Carbamate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the carbamate kinase family.
 
  
 0.773
CCH88704.1
Purine catabolism regulator-like protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; regulator.
 
     0.753
bar
Barbiturase; Responsible for the hydrolysis of barbituric acid (2,4,6- trihydroxy-1,3-pyrimidine), an intermediate in the oxidative catabolism of pyrimidines. Catalyzes the hydrolytic opening of the pyrimidine ring of barbituric acid to yield ureidomalonic acid; Belongs to the cyclic amide hydrolase (CyAH) family.
 
     0.750
coxL
Carbon-monoxide dehydrogenase, molybdopterin binding, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
   
 0.746
coxM
Carbon monoxide dehydrogenase, FAD-binding, medium subunit; Function of strongly homologous gene; enzyme.
 
     0.730
sucB
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; Function of strongly homologous gene; enzyme.
  
 
 0.721
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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