STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
barBarbiturase; Responsible for the hydrolysis of barbituric acid (2,4,6- trihydroxy-1,3-pyrimidine), an intermediate in the oxidative catabolism of pyrimidines. Catalyzes the hydrolytic opening of the pyrimidine ring of barbituric acid to yield ureidomalonic acid; Belongs to the cyclic amide hydrolase (CyAH) family. (367 aa)    
Predicted Functional Partners:
arcC
Carbamate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the carbamate kinase family.
     0.909
hyuB
N-methylhydantoinase B/acetone carboxylase, alpha subunit; Function of strongly homologous gene; enzyme.
 
     0.796
hyuA
N-methylhydantoinase A/acetone carboxylase, beta subunit; Function of strongly homologous gene; enzyme.
 
     0.794
CCH88704.1
Purine catabolism regulator-like protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; regulator.
 
     0.765
CCH85640.1
Homologs of previously reported genes of unknown function.
 
     0.755
sucD
Succinyl-CoA synthetase, alpha subunit; Function of strongly homologous gene; enzyme.
 
     0.750
coxL
Carbon-monoxide dehydrogenase, molybdopterin binding, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
     0.744
coxG
Carbon monoxide dehydrogenase subunit G; Function of strongly homologous gene; cell process.
 
     0.728
CCH88706.1
Homologs of previously reported genes of unknown function.
 
     0.616
CCH86117.1
Homologs of previously reported genes of unknown function.
  
     0.580
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.